Evidence map›Paper›PMID 31944178›Full record

ArticleeLife2020

Muscle function and homeostasis require cytokine inhibition of AKT activity in

Katrin Kierdorf, Fabian Hersperger, Jessica Sharrock, Crystal M Vincent, Pinar Ustaoglu, Jiawen Dou, Attila Gyoergy, Olaf Groß, Daria E Siekhaus, Marc S Dionne

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Macrophage restriction inScience advances · 2026
    Article
  2. Article
  3. Metabolic Regulation in the Maintenance ofInternational journal of molecular sciences · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Microbial metabolism disrupts cytokine activity to impact host immune response.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. METTL14 Regulates Intestine Cellular Senescence through mOxidative medicine and cellular longevity · 2022
    Article
  12. Article
  13. Frontiers in immunology · 2022
    Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Katrin KierdorfMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.ORCID 0000-0002-9272-4780
Fabian HerspergerInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Jessica SharrockMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Crystal M VincentMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Pinar UstaogluMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.
Jiawen DouMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.ORCID 0000-0002-2592-4723
Attila GyoergyInstitute of Science and Technology, Klosterneuburg, Austria.ORCID 0000-0002-1819-198X
Olaf GroßInstitute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Daria E SiekhausInstitute of Science and Technology, Klosterneuburg, Austria.ORCID 0000-0001-8323-8353
Marc S DionneMRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, United Kingdom.ORCID 0000-0002-8283-1750
Imperial College London · GBInstitute of Science and Technology Austria · ATUniversity of Freiburg · DE

Funding

Biotechnology and Biological Sciences Research Council BB/L020122/2Biotechnology and Biological Sciences Research Council BB/L502169/1Biotechnology and Biological Sciences Research Council BB/P000592/1Medical Research Council MR/L018802/2Medical Research Council MR/P028225/1Medical Research Council MR/R00997X/1Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Drosophila ProteinsProto-Oncogene Proteins c-aktReceptors, InterleukinAnimalsAnimals, Genetically ModifiedCytokinesDrosophilaHomeostasisJanus KinasesMaleMusclesSignal TransductionSTAT Transcription FactorsCytokinesdome protein, DrosophilaDrosophila ProteinsJanus KinasesProto-Oncogene Proteins c-aktReceptors, InterleukinSTAT Transcription Factorsdevelopmental biologyD. melanogasterimmunologyinflammationinsulin/AKTJAK/STATmacrophagesmetabolismmuscleplasmatocytes

Identifiers

PMID31944178
PMCPMC6996930
OpenAlexW3000120630

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.