Evidence map›Paper›PMID 31944153›Full record

ArticleRNA biology2020

YB-3 substitutes YB-1 in global mRNA binding.

D N Lyabin, I A Eliseeva, E A Smolin, A N Doronin, K S Budkina, I V Kulakovskiy, L P Ovchinnikov

Open access · greenAbstract read
In one paragraph

Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 42 citations in OpenAlex.

  1. YBX1 regulates RNA polymerase III transcripts to prevent inflammation.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  5. Review
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  8. Y-box binding proteins in immunity and RNA virus infection.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  9. Article
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  12. Article
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  14. Review
  15. Article
  16. Y-Box-Binding Proteins Have a Dual Impact on Cellular Translation.International journal of molecular sciences · 2024
    Article
  17. Article
  18. YB-1 activating cascades as potential targets in KRAS-mutated tumors.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

D N LyabinInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.ORCID 0000-0003-4605-8884
I A EliseevaInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
E A SmolinInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
A N DoroninInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
K S BudkinaInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
I V KulakovskiyVavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
L P OvchinnikovInstitute of Protein Research, Russian Academy of Sciences, Pushchino, Russia.
Institute of Protein Research · RUEngelhardt Institute of Molecular Biology · RUInstitute of Immunological Engineering · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Y-box binding proteins are DNA- and RNA-binding proteins with an evolutionarily ancient and conserved cold shock domain. The Y-box binding protein 1 (YB-1) is the most studied due to its abundance in somatic cells. YB-1 is involved in a variety of cellular processes, including proliferation, differentiation and stress response. Here, using Ribo-Seq and RIP-Seq we confirm that YB-1 binds a wide range of mRNAs and globally acts as a translation inhibitor. Surprisingly,

Indexed as

CCAAT-Enhancer-Binding ProteinsGene Expression ProfilingGene Expression RegulationGene Knockout TechniquesHeat-Shock ProteinsHEK293 CellsHigh-Throughput Nucleotide SequencingHumansProtein BiosynthesisRibosomesRNA, MessengerY-Box-Binding Protein 1CCAAT-Enhancer-Binding ProteinsHeat-Shock ProteinsRNA, MessengerY-Box-Binding Protein 1YBX1 protein, humanYBX3 protein, humanRibo-SeqRIP-Seqtranslational controlYB-1YB-3YBX1YBX3

Identifiers

PMID31944153
PMCPMC7237157
OpenAlexW2999885020

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.