Evidence map›Paper›PMID 31943972›Full record

ArticleACR open rheumatology2020

Budget Impact of Funding an Intensive Diet and Exercise Program for Overweight and Obese Patients With Knee Osteoarthritis.

Karen C Smith, Elena Losina, Stephen P Messier, David J Hunter, Angela T Chen, Jeffrey N Katz, A David Paltiel

Abstract read
In one paragraph

Article in ACR open rheumatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Karen C SmithOrthopedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, Massachusetts.ORCID https://orcid.org/0000-0003-0330-1610
Elena LosinaOrthopedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, Massachusetts.ORCID https://orcid.org/0000-0002-3424-0892
Stephen P MessierJ.B. Snow Biomechanics Laboratory, Wake Forest University, Winston-Salem, North Carolina.
David J HunterUniversity of Sydney, Sydney, Australia.
Angela T ChenOrthopedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, Massachusetts.
Jeffrey N KatzOrthopedic and Arthritis Center for Outcomes Research (OrACORe), Brigham and Women's Hospital, Boston, Massachusetts.ORCID https://orcid.org/0000-0003-2104-4670
A David PaltielYale School of Public Health, New Haven, Connecticut.

Funding

VERITY: Value and Evidence in Rheumatology using bioInformaTics, and advanced analYticsP30AR072577 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Katherine Phoenix Liao · 2017 to 2026
$9.8M
Optimizing the value of pain management in knee OA patients with comorbiditiesR01AR074290 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI Elena Losina · 2018 to 2026
$5.9M
Clinical impact and cost-effectiveness of pain management in knee OAR01AR064320 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LOSINA, ELENA · 2013 to 2017
$3.3M
Patient Oriented Research and Mentoring Program in OrthopedicsK24AR057827 · NIAMS · BRIGHAM AND WOMEN'S HOSPITAL · PI LOSINA, ELENA · 2010 to 2019
$1.7M
NIAMS NIH HHS K24 AR057827NIAMS NIH HHS K24-AR-057827NIAMS NIH HHS P30 AR072577NIAMS NIH HHS P30-AR-072577NIAMS NIH HHS R01 AR064320NIAMS NIH HHS R01-AR-064320NIAMS NIH HHS R01 AR074290NIAMS NIH HHS R01-AR-074290
6 · The paper itself

Abstract

objectiveDiet and exercise (D+E) for knee osteoarthritis (OA) is effective and cost-effective. However, cost-effectiveness does not imply affordability; the impact of knee OA-specific D+E programs on insurer budgets is unknown.

methodsWe estimated changes in undiscounted medical expenditures (2016 US dollars) with and without a D+E program. We accounted for both additional program outlays and potential savings from reduced use of other knee OA treatments and from reduced incidence of comorbidities. We adopted the perspective of a representative commercial insurance plan covering 200 000 individuals aged 25 to 64 years and a representative Medicare Advantage plan covering 200 000 Medicare-eligible individuals aged 65 years and older. We used the Osteoarthritis Policy Model, a validated microsimulation model of knee OA, to model D+E efficacy (measured by pain and weight reduction), adherence, and price based on the Intensive Diet and Exercise for Arthritis (IDEA) trial. In sensitivity analyses, we varied time horizon, D+E efficacy, and D+E price.

resultsOver 3 years, the D+E program increased spending by $752 200 ($0.10 per member per month [PMPM]) in the commercial plan and by $6.0 million ($0.84 PMPM) in the Medicare plan. Over 3 years, the D+E program reduced opioid use by 6% and 5% and reduced total knee replacements by 5% and 4% in the commercial and Medicare plans, respectively. Expenses were higher in the Medicare plan because it had more patients with knee OA than the commercial plan.

conclusionAlthough there is no established threshold to define affordability, a D+E program for knee OA would likely produce expenditures comparable with outlays for other health-promotion interventions.

Identifiers

PMID31943972
PMCPMC6957917

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.