Evidence map›Paper›PMID 31943946›Full record

ArticleAnnals of clinical and translational neurology2020

An expanded parenchymal CD8+ T cell clone in GABA

Aline Bracher, Carmen Alcalá, Jaime Ferrer, Nico Melzer, Reinhard Hohlfeld, Bonaventura Casanova, Eduardo Beltrán, Klaus Dornmair

Open access · goldAbstract readCase Reports
In one paragraph

Article in Annals of clinical and translational neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Immune cell profiling reveals expanded stem cell-like memory T cells in anti-GAD65-associated neurological syndromes.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Autoimmune encephalitis-associated epilepsy.Nature reviews. Neurology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. The neurovasculature as a target in temporal lobe epilepsy.Brain pathology (Zurich, Switzerland) · 2023
    Review
  8. GABAInternational journal of molecular sciences · 2022
    Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABAProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Aline BracherInstitute of Clinical Neuroimmunology, Biomedical Center and Hospital of the Ludwig-Maximilians Universität München, Munich, Germany.
Carmen AlcaláDepartment of Neurology, Hospital Universitari i Politècnic la Fe, Valencia, Spain.
Jaime FerrerDepartment of Pathology, Hospital Universitari i Politècnic la Fe, Valencia, Spain.
Nico MelzerClinic of Neurology and Institute of Translational Neurology, University Hospital Münster, Münster, Germany.
Reinhard HohlfeldInstitute of Clinical Neuroimmunology, Biomedical Center and Hospital of the Ludwig-Maximilians Universität München, Munich, Germany.
Bonaventura CasanovaDepartment of Neurology, Hospital Universitari i Politècnic la Fe, Valencia, Spain.ORCID 0000-0003-3806-925X
Eduardo BeltránInstitute of Clinical Neuroimmunology, Biomedical Center and Hospital of the Ludwig-Maximilians Universität München, Munich, Germany.
Klaus DornmairInstitute of Clinical Neuroimmunology, Biomedical Center and Hospital of the Ludwig-Maximilians Universität München, Munich, Germany.ORCID 0000-0003-0342-5373
Hospital Universitari i Politècnic La Fe · ESLudwig-Maximilians-Universität München · DEMunich Cluster for Systems Neurology · DEUniversity Hospital Münster · DE

Funding

the German Research Councilthe Munich Cluster for Systems Neurology 390857198Wilhelm Sander Foundation 2011.113.1Wilhelm Sander Foundation 2011.113.2
6 · The paper itself

Abstract

The role of T cells in autoimmune encephalitis syndromes with autoantibodies against cell surface antigens is still enigmatic. Here we analyzed the T cell receptor repertoires of CD8+ and CD4+ T cells in a patient with "idiopathic" gamma-aminobutyric-acid-A receptor (GABA

Indexed as

CD8-Positive T-LymphocytesAutoantibodiesAutoimmune Diseases of the Nervous SystemAutopsyCD4-Positive T-LymphocytesClone CellsEncephalitisHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedReceptors, GABA-AAutoantibodiesReceptors, GABA-A

Identifiers

PMID31943946
PMCPMC7034500
OpenAlexW2999487375

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.