Evidence map›Paper›PMID 31943589›Full record

ArticleChembiochem : a European journal of chemical biology2020

Structure Validation of G-Rich RNAs in Noncoding Regions of the Human Genome.

Oliver Binas, Irene Bessi, Harald Schwalbe

Open access · hybridAbstract readValidation Study
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. G-Quadruplexes in Repeat Expansion Disorders.International journal of molecular sciences · 2023
    Review
  8. Insights from Binding on Quadruplex Selective Carbazole Ligands.Chemistry (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  9. Review
  10. Article
  11. Structure Validation of G-Rich RNAs in Noncoding Regions of the Human Genome.Chembiochem : a European journal of chemical biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Oliver BinasInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt, Germany.
Irene BessiInstitute for Organic and Biomolecular Chemistry, Julius Maximilians University Würzburg, Am Hubland, 97074, Würzburg, Germany.
Harald SchwalbeInstitute for Organic Chemistry and Chemical Biology, Goethe University Frankfurt, Max-von-Laue Strasse 7, 60438, Frankfurt, Germany.ORCID 0000-0001-5693-7909
Goethe University Frankfurt · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the rapid biophysical characterization of six previously reported putative G-quadruplex-forming RNAs from the 5'-untranslated region (5'-UTR) of silvestrol-sensitive transcripts for investigation of their secondary structures. By NMR and CD spectroscopic analysis, we found that only a single sequence-[AGG]

Indexed as

G-QuadruplexesADAM10 ProteinAmyloid Precursor Protein SecretasesBenzofuransE1A-Associated p300 ProteinGenome, HumanHistone DeacetylasesHumansIntracellular Signaling Peptides and ProteinsMAP-Kinase-Activated Kinase 2Membrane ProteinsPoly GProtein Serine-Threonine KinasesRepressor ProteinsRNA FoldingRNA, MessengerADAM10 ProteinADAM10 protein, humanAmyloid Precursor Protein SecretasesBenzofuransE1A-Associated p300 ProteinEP300 protein, humanHistone DeacetylasesIntracellular Signaling Peptides and ProteinsMAP-Kinase-Activated Kinase 2Membrane ProteinsMTA2 protein, humanPoly GProtein Serine-Threonine KinasesRepressor ProteinsRNA, MessengerRNA, UntranslatedsilvestrolTGFB1 protein, humanTransforming Growth Factor beta1Triterpenesbiophysical investigationcircular dichroismG-quadruplexesNMR spectroscopyRNA

Identifiers

PMID31943589
PMCPMC7318348
OpenAlexW2999131819

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.