Evidence map›Paper›PMID 31943221›Full record

ArticleMedical physics2020

SciFi detector and associated method for real-time determination of profile and output factor for small fields in stereotactic radiotherapy.

P Pittet, J Esteves, J-M Galvan, G-N Lu, F Blanc, G Haefeli, P Hopchev, S Rit, L Desbat, J Ribouton and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

P PittetInstitut des Nanotechnologies de Lyon INL, CNRS UMR5270, Université de Lyon, Université Claude Bernard Lyon 1, F-69100, Villeurbanne, France.
J EstevesInstitut des Nanotechnologies de Lyon INL, CNRS UMR5270, Université de Lyon, Université Claude Bernard Lyon 1, F-69100, Villeurbanne, France.
J-M GalvanInstitut des Nanotechnologies de Lyon INL, CNRS UMR5270, Université de Lyon, Université Claude Bernard Lyon 1, F-69100, Villeurbanne, France.
G-N LuInstitut des Nanotechnologies de Lyon INL, CNRS UMR5270, Université de Lyon, Université Claude Bernard Lyon 1, F-69100, Villeurbanne, France.
F BlancLaboratoire de Physique des Hautes Energies LPHE, EPFL, CH-1015, Lausanne, Switzerland.
G HaefeliLaboratoire de Physique des Hautes Energies LPHE, EPFL, CH-1015, Lausanne, Switzerland.
P HopchevLaboratoire de Physique des Hautes Energies LPHE, EPFL, CH-1015, Lausanne, Switzerland.
S RitUniversity Lyon, INSA-Lyon, Université Claude Bernard Lyon 1, CNRS UMR 5220, Inserm U1206, CREATIS, Lyon, France.
L DesbatUniversity Grenoble Alpes, CNRS, Grenoble INP, TIMC-IMAG, F-38000, Grenoble, France.
J RiboutonService de Radiophysique et Radiovigilance, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, F-69495, Pierre-Bénite, France.
P JaladeService de Radiophysique et Radiovigilance, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, F-69495, Pierre-Bénite, France.
École Polytechnique Fédérale de Lausanne · CHHôpital Lyon Sud · FRInstitut des Nanotechnologies de Lyon · FRUniversité Claude Bernard Lyon 1 · FRCentre National de la Recherche Scientifique · FRUniversité Grenoble Alpes · FR

Funding

Investissements d'Avenir ANR-11-IDEX-0007ITMO Cancer AVIESANLABEX PRIMES ANR-11-LABX-0063Swiss National Science Foundation
6 · The paper itself

Abstract

purposeFor determining small-field profile and output factor during stereotactic radiotherapy quality assurance (QA) procedures, we propose a novel system based on the scintillating fiber (SciFi) detector with output image acquisition and processing to allow real-time monitoring of profile and output factor. MATERIALS AND

methodsThe employed detector is a SciFi detector made of tissue-equivalent scintillating plastic fibers arranged in 6-layer fiber ribbons with a fiber pitch of 275 μm in each layer. The scintillating signal at the detector output is acquired by a sCMOS (scientific complementary metal-oxide-semiconductor) camera and represents the projected field profile along the fibers axis. An iterative reconstruction method of the field from its projected profile based on a priori knowledge of some features of the radiation field defined by the stereotactic cones is suggested. The detector with implemented data processing has been tested in clinical conditions, for determining beam profiles and output factors, using cone collimators of different sizes from 4 to 15 mm diameter. The detector under test was placed at 1.4 cm depth and 98.6 cm source to surface distance (SSD) in a water-equivalent phantom and irradiated by a 6 MV photon beam.

resultsThe reconstructed field profiles obtained from the detector are coherent with data from EBT3 radiochromic films, with differences within ±0.32 mm for both the FWHM and the penumbra region. For real-time determination of the field output factor, the measured data are also in good agreement with data independently determined by the French Institute for Radiological Protection and Nuclear Safety (IRSN) based on radiochromic films and thermoluminescent 1 × 1 mm

conclusionsWe propose and have tested a SciFi plastic scintillating detector with an optimized signal processing method to characterize small fields defined by cone collimators. It allows the determination of key field parameters such as full width at half maximum (FWHM) and field output factors. The results are consistent with those independently measured using TLD and radiochromic films. As the SciFi detector does not require a correction factor, it is in line with the International Atomic Energy Agency (IAEA) and the American Association of Physicists in Medicine (AAPM) TRS-483 recommendations, and can be suitable for online QA of small radiation fields used in photon beam radiotherapy, and is compatible with MRI-LINAC.

Indexed as

Particle AcceleratorsRadiosurgeryRadiotherapy DosageScintillation CountingTime Factorsscintillating detectorssmall-field dosimetry

Identifiers

PMID31943221
PMCPMC7216919
OpenAlexW2999436525

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.