Evidence map›Paper›PMID 31942825›Full record

SynthesisGut microbes2020

Systematic review of human gut resistome studies revealed variable definitions and approaches.

Jeffery Ho, Yun Kit Yeoh, Nilakshi Barua, Zigui Chen, Grace Lui, Sunny H Wong, Xiao Yang, Martin Cw Chan, Paul Ks Chan, Peter M Hawkey and 1 more

Abstract readSystematic Review
In one paragraph

Synthesis in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Bacterial Urban Resistome: Recent Advances.Antibiotics (Basel, Switzerland) · 2022
    Review
  12. A review of the resistome within the digestive tract of livestock.Journal of animal science and biotechnology · 2021
    Review
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jeffery HoDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.
Yun Kit YeohDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0003-0241-6117
Nilakshi BaruaDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0002-7007-5433
Zigui ChenDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0002-8577-1298
Grace LuiCentre for Gut Microbiota Research, The Chinese University of Hong Kong , Hong Kong SAR, China.
Sunny H WongCentre for Gut Microbiota Research, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0002-3354-9310
Xiao YangDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0002-3071-6531
Martin Cw ChanDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0002-1568-1596
Paul Ks ChanDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0002-6360-4608
Peter M HawkeyInstitute of Microbiology and Infection, University of Birmingham , Birmingham, UK.
Margaret IpDepartment of Microbiology, The Chinese University of Hong Kong , Hong Kong SAR, China.ORCID 0000-0003-1291-6537

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this review, we highlight the variations of gut resistome studies, which may preclude comparisons and translational interpretations. Of 22 included studies, a range of 12 to 2000 antibiotic resistance (AR) genes were profiled. Overall, studies defined a healthy gut resistome as subjects who had not taken antibiotics in the last three to 12 months prior to sampling. In studies with

Indexed as

Anti-Bacterial AgentsBacteriaDrug Resistance, BacterialGastrointestinal MicrobiomeGastrointestinal TractGenes, BacterialHumansAnti-Bacterial Agentsantibiotic resistancefecal microbiota transplantationgut microbiotameta-genomicsResistome

Identifiers

PMID31942825
PMCPMC7524153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.