ArticleJournal of experimental botany2020
Three previously characterized resistances to yellow rust are encoded by a single locus Wtk1.
Article in Journal of experimental botany, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 33 citations in OpenAlex.
- Gb3 encodes a unique kinase fusion protein conferring greenbug resistance in wheat.Nature genetics · 2026Article
- An HMA-like integrated domain in the wheat tandem kinase WTK4 recognises an RNase-like pathogen effector.Nature communications · 2026Article
- Genetic diversity and genome-wide association study of yellow rust resistance in elite spring bread wheat genotypes in Ethiopia.BMC genomics · 2025Article
- Durum wheat mutants with enhanced disease resistance to stripe rust show differential responses to other fungal diseases.Molecular breeding : new strategies in plant improvement · 2025Article
- A major yellow rust resistance QTL on chromosome 6A shows increased frequency in recent Norwegian spring wheat cultivars and breeding lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Unraveling the diversity and functions of sugar transporters for sustainable management of wheat rust.Functional & integrative genomics · 2023Review
- Comparison of linear and semi-parametric models incorporating genomic, pedigree, and associated loci information for the prediction of resistance to stripe rust in an Austrian winter wheat breeding program.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Genetic architecture of adult-plant resistance to stripe rust in bread wheat (Frontiers in plant science · 2023Article
- Discovery of stripe rust resistance with incomplete dominance in wild emmer wheat using bulked segregant analysis sequencing.Communications biology · 2022Article
- The evolving battle between yellow rust and wheat: implications for global food security.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Review
- Capturing Wheat Phenotypes at the Genome Level.Frontiers in plant science · 2022Review
- Wheat genetic loci conferring resistance to stripe rust in the face of genetically diverse races of the fungus Puccinia striiformis f. sp. tritici.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Novel stripe rust all-stage resistance loci identified in a worldwide collection of durum wheat using genome-wide association mapping.The plant genome · 2021Article
- Tandem Protein Kinases Emerge as New Regulators of Plant Immunity.Molecular plant-microbe interactions : MPMI · 2021Review
- TdPm60 identified in wild emmer wheat is an ortholog of Pm60 and constitutes a strong candidate for PmG16 powdery mildew resistance.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Genomic signatures of selection for resistance to stripe rust in Austrian winter wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
- Genome-wide association mapping identifies yellow rust resistance loci in Ethiopian durum wheat germplasm.PloS one · 2021Article
- A Post-Haustorial Defense Mechanism is Mediated by the Powdery Mildew Resistance Gene,Pathogens (Basel, Switzerland) · 2020Article
- Distribution and Nucleotide Diversity ofPathogens (Basel, Switzerland) · 2020Article
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The wild emmer wheat (Triticum turgidum ssp. dicoccoides; WEW) yellow (stripe) rust resistance genes Yr15, YrG303, and YrH52 were discovered in natural populations from different geographic locations. They all localize to chromosome 1B but were thought to be non-allelic based on differences in resistance response. We recently cloned Yr15 as a Wheat Tandem Kinase 1 (WTK1) and show here that these three resistance loci co-segregate in fine-mapping populations and share an identical full-length genomic sequence of functional Wtk1. Independent ethyl methanesulfonate (EMS)-mutagenized susceptible yrG303 and yrH52 lines carried single nucleotide mutations in Wtk1 that disrupted function. A comparison of the mutations for yr15, yrG303, and yrH52 mutants showed that while key conserved residues were intact, other conserved regions in critical kinase subdomains were frequently affected. Thus, we concluded that Yr15-, YrG303-, and YrH52-mediated resistances to yellow rust are encoded by a single locus, Wtk1. Introgression of Wtk1 into multiple genetic backgrounds resulted in variable phenotypic responses, confirming that Wtk1-mediated resistance is part of a complex immune response network. WEW natural populations subjected to natural selection and adaptation have potential to serve as a good source for evolutionary studies of different traits and multifaceted gene networks.
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