ArticleGigaScience2020
A draft genome sequence of the elusive giant squid, Architeuthis dux.
Article in GigaScience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 76 citations in OpenAlex.
- DOO: integrated multi-omics resources for deep ocean organisms.Nucleic acids research · 2026Article
- Giant genome of the vampire squid reveals the derived state of modern octopod karyotypes.iScience · 2025Article
- Characterization of C2H2 superfamily expansions in cephalopods and their contribution to nervous system evolution.iScience · 2025Article
- Cephalopod sex determination and its ancient evolutionary origin.Current biology : CB · 2025Article
- A chromosome-level genome for the nudibranch gastropod Berghia stephanieae helps parse clade-specific gene expression in novel and conserved phenotypes.BMC biology · 2024Article
- The neural basis of visual processing and behavior in cephalopods.Current biology : CB · 2023Review
- De novo genome assembly and comparative genomics for the colonial ascidian Botrylloides violaceus.G3 (Bethesda, Md.) · 2023Article
- Whole-genome Analyses Reveal Past Population Fluctuations and Low Genetic Diversities of the North Pacific Albatrosses.Molecular biology and evolution · 2023Article
- Article
- Article
- Article
- Genomes of Two Flying Squid Species Provide Novel Insights into Adaptations of Cephalopods to Pelagic Life.Genomics, proteomics & bioinformatics · 2022Article
- Gene Recruitments and Dismissals in the Argonaut Genome Provide Insights into Pelagic Lifestyle Adaptation and Shell-like Eggcase Reacquisition.Genome biology and evolution · 2022Article
- Epigenetic machinery is functionally conserved in cephalopods.BMC biology · 2022Article
- Identification of LINE retrotransposons and long non-coding RNAs expressed in the octopus brain.BMC biology · 2022Article
- Repeat Age Decomposition Informs an Ancient Set of Repeats Associated With Coleoid Cephalopod Divergence.Frontiers in genetics · 2022Article
- Sticky problems: extraction of nucleic acids from molluscs.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Mobilizing molluscan models and genomes in biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Article
- Non-collinear Hox gene expression in bivalves and the evolution of morphological novelties in mollusks.Scientific reports · 2021Article
- The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia.BMC biology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
44 authors at 20 institutions in 20 countries.
Funding
Abstract
backgroundThe giant squid (Architeuthis dux; Steenstrup, 1857) is an enigmatic giant mollusc with a circumglobal distribution in the deep ocean, except in the high Arctic and Antarctic waters. The elusiveness of the species makes it difficult to study. Thus, having a genome assembled for this deep-sea-dwelling species will allow several pending evolutionary questions to be unlocked.
findingsWe present a draft genome assembly that includes 200 Gb of Illumina reads, 4 Gb of Moleculo synthetic long reads, and 108 Gb of Chicago libraries, with a final size matching the estimated genome size of 2.7 Gb, and a scaffold N50 of 4.8 Mb. We also present an alternative assembly including 27 Gb raw reads generated using the Pacific Biosciences platform. In addition, we sequenced the proteome of the same individual and RNA from 3 different tissue types from 3 other species of squid (Onychoteuthis banksii, Dosidicus gigas, and Sthenoteuthis oualaniensis) to assist genome annotation. We annotated 33,406 protein-coding genes supported by evidence, and the genome completeness estimated by BUSCO reached 92%. Repetitive regions cover 49.17% of the genome.
conclusionsThis annotated draft genome of A. dux provides a critical resource to investigate the unique traits of this species, including its gigantism and key adaptations to deep-sea environments.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.