Evidence map›Paper›PMID 31942563›Full record

ArticleAnimal models and experimental medicine2019

Therapeutic effects of

Ejeh Augustine Sunday, Patrick Azubuike Onyeyili, Saganuwan Alhaji Saganuwan

Open access · diamondAbstract read
In one paragraph

Article in Animal models and experimental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 10 citations in OpenAlex.

  1. Therapeutic effects ofAnimal models and experimental medicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Ejeh Augustine SundayDepartment of Veterinary Physiology and Biochemistry Faculty of Veterinary Medicine University of Abuja FCT Nigeria.
Patrick Azubuike OnyeyiliDepartment of Veterinary Pharmacology and Toxicology College of Veterinary Medicine Federal University of Agriculture Makurdi Benue State Nigeria.
Saganuwan Alhaji SaganuwanDepartment of Veterinary Pharmacology and Toxicology College of Veterinary Medicine Federal University of Agriculture Makurdi Benue State Nigeria.ORCID https://orcid.org/0000-0002-0963-5569
Federal University of Agriculture · NGUniversity of Abuja · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiarrhea can be caused by pathogenic microorganisms and chemicals. In view of this,

methodsQualitative and quantitative analyses of an aqueous root back extract of

resultsThe phytochemical analysis of the root bark extract revealed the presence of flavonoids, alkaloid, saponins, tannins, and phenols. The quantitative analysis showed that saponins formed 10.6% of the extract, tannins 7.6%, flavonoids 6.2%, phenol 5.8% and alkaloids 4.4%. A dose limit of 5000 mg/kg was safe to use in the rats. At a dose of 100 mg/kg, the extract decreased distance travelled by activated charcoal in the gastrointestinal tract, frequency of defecation, and number of unformed faeces caused by castor oil-induced diarrhea, and led to 74.96% inhibition of the diarrhea effects.

conclusion

Indexed as

antidiarrhoeaBryocarpus coccineuscastor oildiarrheaE. coliextracthematonicrat

Identifiers

PMID31942563
PMCPMC6930995
OpenAlexW2996052866

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.