ArticleAging medicine (Milton (N.S.W))2019
Who has the guts to deprescribe proton pump inhibitors? A pharmacist-led intervention in a long-term care facility setting.
Article in Aging medicine (Milton (N.S.W)), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A systematic review and meta-analysis on pharmacist-led interventions for the management of peptic ulcer disease.PloS one · 2025Pooled it
- Systematic review and narrative synthesis of pharmacist provided medicines optimisation services in care homes for older people to inform the development of a generic training or accreditation process.The International journal of pharmacy practice · 2020Pooled it
- Deprescribing proton pump inhibitors in long-term care: Outcomes of a pharmacist-led initiative.Exploratory research in clinical and social pharmacy · 2026Article
- Deprescribing Antipsychotics and Proton Pump Inhibitors in Long-Term Care: A Prescribing Portraits Approach.Drugs & aging · 2025Article
- Pharmacist-Mediated Deprescribing in Long-Term Care Facilities: A Systematic Review.Pharmacy (Basel, Switzerland) · 2025Review
- Approaches to Deprescribing Proton Pump Inhibitors in Clinical Practice: A Systematic Review.Journal of clinical medicine · 2024Review
- Determinants of and interventions for Proton Pump Inhibitor prescription behavior: A systematic scoping review.BMC primary care · 2024Article
- Deprescribing of proton pump inhibitors in older patients: A cost-effectiveness analysis.PloS one · 2024Article
- Prescribing Portraits to Optimize Prescribing of Proton Pump Inhibitors in Long-Term Care: PPI-T STOP Study.The Canadian journal of hospital pharmacy · 2024Article
- A pharmacist-led medication review service with a deprescribing focus guided by implementation science.Frontiers in pharmacology · 2023Article
- Appropriateness and Associated Factors of Stress Ulcer Prophylaxis for Surgical Inpatients of Orthopedics Department in a Tertiary Hospital: A Cross-Sectional Study.Frontiers in pharmacology · 2022Article
- Discussing proton pump inhibitor deprescribing: the views of Danish GPs and older patients.BMC family practice · 2020Article
- Who has the guts to deprescribe proton pump inhibitors? A pharmacist-led intervention in a long-term care facility setting.Aging medicine (Milton (N.S.W)) · 2019Article
- Deprescribing practices in Canada: A scoping review.Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPCArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveLong-term use of proton pump inhibitors (PPIs) has been associated with an increased risk of harm. There are few studies evaluating pharmacist-led PPI deprescribing interventions within a long-term care facility setting. The aim of this study was to describe the changes and influencing factors seen with a pharmacist-led PPI deprescribing intervention in two Fraser Health Authority long-term care facilities in British Columbia.
methodsThis 4-month intervention involved lists of residents who had active PPI orders being handed out to physicians from two facilities. The pharmacist conducted weekly reviews of residents from Facility 1 and offered deprescribing recommendations. The number and methods of PPI deprescribing orders per facility were determined after the intervention.
resultsOut of 58 residents from the two facilities, 30 (62.5%) had a deprescribing order. Facility 1 had 83.3% (20/24) of residents with a PPI deprescribing order, in contrast to 41.7% (10/24) from Facility 2. Overall, 80.0% of residents had successfully completed PPI deprescribing orders by the end of the study period.
conclusionClinical pharmacist intervention may increase the rate of initiation in PPI deprescribing orders within a long-term care facility setting. Factors that influence success include intervention timing, active collaboration, having residents under direct care, and clear documentation of PPI indications.
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