Evidence map›Paper›PMID 31942499›Full record

ArticleAging medicine (Milton (N.S.W))2018

Functional MRI on executive functioning in aging and dementia: A scoping review of cognitive tasks.

Andrew P McDonald, Ryan C N D'Arcy, Xiaowei Song

Abstract readScoping Review
In one paragraph

Article in Aging medicine (Milton (N.S.W)), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  13. Cerebral blood flow in patients recovered from mild COVID-19.Journal of neuroimaging : official journal of the American Society of Neuroimaging
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew P McDonaldHealth Sciences and Innovation Fraser Health Authority Surrey British Columbia Canada.
Ryan C N D'ArcyHealth Sciences and Innovation Fraser Health Authority Surrey British Columbia Canada.
Xiaowei SongHealth Sciences and Innovation Fraser Health Authority Surrey British Columbia Canada.ORCID 0000-0001-9589-2520

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive decline with aging and dementia is especially poignant with regard to the executive functioning that is necessary for activities of daily independent living. The relationship between age-related neurodegeneration in the prefrontal cortex and executive functioning has been uniquely investigated using task-phase functional magnetic resonance imaging (fMRI) to detect brain activity in response to stimuli; however, a comprehensive list of task designs that have been implemented to task-phase fMRI is absent in the literature. The purpose of this review was to recognize what methods have been used to study executive functions with aging and dementia in fMRI tasks, and to describe and categorize them. The following cognitive subdomains were emphasized: cognitive flexibility, planning and decision-making, working memory, cognitive control/inhibition, semantic processing, attention and concentration, emotional functioning, and multitasking. Over 30 different task-phase fMRI designs were found to have been implemented in the literature, all adopted from standard neuropsychological assessments. Cognitive set-shifting and decision-making tasks were particularly well studied in regard to age-related neurodegeneration, while emotional functioning and multitasking designs were found to be the least utilized. Summarizing the information on which tasks have shown the greatest usability will assist in the future design and implementation of effective fMRI experiments targeting executive functioning.

Indexed as

brain aging and dementiaexecutive functionmild cognitive impairmentneuropsychological taskstask‐phase fMRI

Identifiers

PMID31942499
PMCPMC6880681

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.