Evidence map›Paper›PMID 31942444›Full record

ArticleACS biomaterials science & engineering2019

Evaluation of PEG-based hydrogel influence on estrogen receptor driven responses in MCF7 breast cancer cells.

Megan K Livingston, Molly M Morgan, William T Daly, William L Murphy, Brian P Johnson, David J Beebe, Maria Virumbrales-Muñoz

Abstract read
In one paragraph

Article in ACS biomaterials science & engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Living Hydrogels: Harnessing Microorganism-Material Synergy for Next-Generation Therapeutics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  7. Synthetic alternatives to Matrigel.Nature reviews. Materials · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Megan K LivingstonDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706.
Molly M MorganSchool of Medicine and Public Health, University of Wisconsin-Madison, 750 Highland Ave, Madison, WI 53726.
William T DalyDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, 1111 Highland Ave, Madison, WI 55705.
William L MurphyDepartment of Orthopedics and Rehabilitation, University of Wisconsin-Madison, 1111 Highland Ave, Madison, WI 55705.
Brian P JohnsonSchool of Medicine and Public Health, University of Wisconsin-Madison, 750 Highland Ave, Madison, WI 53726.
David J BeebeSchool of Medicine and Public Health, University of Wisconsin-Madison, 750 Highland Ave, Madison, WI 53726.
Maria Virumbrales-MuñozSchool of Medicine and Public Health, University of Wisconsin-Madison, 750 Highland Ave, Madison, WI 53726.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Justine Yang Bruce · 1985 to 2026
$142.6M
Molecular & Environmental Toxicology Pre-& Postdoctoral Training ProgramT32ES007015 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI CHRISTOPHER A BRADFIELD · 1985 to 2026
$11.5M
Biomaterials for local regulation of growth factor signalingR01HL093282 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI MURPHY, WILLIAM L. · 2009 to 2018
$3.3M
An automated high-throughput tissue model for screening metastatic effectorsR01CA186134 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI BEEBE, DAVID J · 2015 to 2019
$3.1M
Elucidating AHR signaling interplay in orofacial clefting and endocrine disruption using microplate microfluidicsK99ES028744 · NIEHS · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, BRIAN P. · 2018 to 2019
$200k
Intramural EPA EPA999999NCI NIH HHS P30 CA014520NCI NIH HHS R01 CA186134NHLBI NIH HHS R01 HL093282NIEHS NIH HHS K99 ES028744NIEHS NIH HHS T32 ES007015
6 · The paper itself

Abstract

Extracellular matrix (ECM) mimicking hydrogel scaffolds have greatly improved the physiological relevance of

Indexed as

collagenECMhydrogelMatrigelPEGvariance

Identifiers

PMID31942444
PMCPMC6961958

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.