Evidence map›Paper›PMID 31942413›Full record

ArticleBalkan journal of medical genetics : BJMG2019

S Demir, M H Müslümanoğlu, M Müslümanoğlu, S Başaran, Z Z Çalay, A Aydıner, U Vogt, T Çakır, H Kadıoğlu, S Artan

Open access · goldAbstract read
In one paragraph

Article in Balkan journal of medical genetics : BJMG, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

S DemirEskişehir Osmangazi University Faculty of Medicine Department of Medical Genetics, Eskişehir, Turkey.
M H MüslümanoğluYıldız Technical University Faculty of Science and Literature Department of Molecular Biology and Genetics, Istanbul, Turkey.
M MüslümanoğluBezmialem University Faculty of Medicine Department of General Surgery, Istanbul, Turkey.
S BaşaranIstanbul University Faculty of Medicine Department of Medical Genetics, Istanbul, Turkey.
Z Z ÇalayIstanbul University Cerrahpaşa Medical Faculty Department of Pathology, Istanbul, Turkey.
A AydınerIstanbul University Faculty of Medicine Department of Medical Oncology, Istanbul, Turkey.
U VogtEuropean Laboratory Association ELA, Ibbenbueren, Germany.
T ÇakırGebze Technical University Faculty of Engineering Department of Bioengineering, Istanbul, Turkey.
H KadıoğluMedicana Hospital, Department of General Surgery, Bahçelievler, İstanbul Turkey.
S ArtanEskişehir Osmangazi University Faculty of Medicine Department of Medical Genetics, Eskişehir, Turkey.
Bezmiâlem Vakıf Üniversitesi · TRGebze Technical University · TRIstanbul University · TREskişehir Osmangazi University · TRTrakya University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Doxorubicin is one of the most commonly used chemotherapeutic agents for adjuvant chemotherapy of breast cancer. In the studies focused on finding biomarkers to predict the response of the patients and tumors to the drugs used, the Twist transcription factor has been suggested as a candidate biomarker for predicting chemo-resistance of breast tumors. In this study, we aimed to investigate the relationship between TWIST transcription factor expression and the effectiveness of doxorubicin treatment on directly taken primary tumor samples from chemotherapy-naive breast cancer patients. Twenty-six primary breast tumor samples taken from 26 different breast cancer patients were included in this study. Adenosine triphosphate tumor chemo-sensitivity assay (ATP-TCA) has been used to determine tumor response to doxorubicin and real-time reverse-transcription polymerase chain reaction (RT-PCR) was used for analyzing the

Indexed as

BiomarkerBreast cancerChemotherapyExpressionTWIST1 gene

Identifiers

PMID31942413
PMCPMC6956638
OpenAlexW2997908426

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.