Evidence map›Paper›PMID 31942262›Full record

ArticleLiquid crystals reviews2019

Lipid-based Liquid Crystalline Films and Solutions for the Delivery of Cargo to Cells.

Marilyn Porras-Gomez, Cecilia Leal

Abstract read
In one paragraph

Article in Liquid crystals reviews, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Polymerization from Lipid Membranes.Biomacromolecules · 2026
    Article
  2. Article
  3. Article
  4. Lipid nanoparticle topology regulates endosomal escape and delivery of RNA to the cytoplasm.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  5. Article
  6. Polymer-Lipid Hybrid Materials.Chemical reviews · 2021
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marilyn Porras-GomezDepartment of Materials Science and Engineering, University of Illinois at Urbana-Champaign. Urbana, IL 61801, USA.
Cecilia LealDepartment of Materials Science and Engineering, University of Illinois at Urbana-Champaign. Urbana, IL 61801, USA.

Funding

A New Paradigm in Nanomedicine: can structural interiors of nanoparticles regulate cellular delivery?DP2EB024377 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LEAL, CECILIA MARIA · 2016 to 2016
$2.3M
NIBIB NIH HHS DP2 EB024377
6 · The paper itself

Abstract

A major challenge in the delivery of cargo (genes and/or drugs) to cells using nanostructured vehicles is the ability to safely penetrate plasma membranes by escaping the endosome before degradation, later releasing the payload into the cytoplasm or organelle of interest. Lipids are a class of bio-compatible molecules that self-assemble into a variety of liquid crystalline constructs. Most of these materials can be used to encapsulate drugs, proteins, and nucleic acids to deliver them safely into various cell types. Lipid phases offer a plethora of structures capable of forming complexes with biomolecules, most notably nucleic acids. The physichochemical characteristics of the lipid molecular building blocks, one might say the lipid

Indexed as

drug deliverygene deliverylipid-based liquid crystalslipid filmslipid particlessmall molecules

Identifiers

PMID31942262
PMCPMC6961842

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.