ArticleNature2020
Host-mediated ubiquitination of a mycobacterial protein suppresses immunity.
Abstract read
In one paragraph
Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 99 citations in OpenAlex.
- Live AirwayEnvironment & health (Washington, D.C.) · 2026Article
- The host ubiquitination system dynamically regulates the inflammatory response of macrophages to bacteria.Frontiers in immunology · 2026Review
- Cell death pathways in response toInfection and immunity · 2025Review
- The Ubiquitination ofBiology · 2025Article
- Mycobacterial Tyrosine Phosphatase PtpB Affects Host Cytokine Expression by Dephosphorylating ERK1/2 and STAT3.Molecular & cellular proteomics : MCP · 2025Article
- SMURF2 inhibits autophagic control ofbioRxiv : the preprint server for biology · 2025Article
- Mycobacterial phthiocerol dimycocerosate induces Galectin-3 upregulation to impair proinflammatory responses and favor immune evasion.International journal of biological macromolecules · 2025Article
- New Advances in the Development and Design ofBiology · 2025Review
- Mycobacterial PstP impairs host RNA alternative splicing by dephosphorylation of spliceosome RBMX at S189.iMetaOmics · 2025Article
- A Pilot Study on the Role of TRAFs in the Development of SARS-CoV-2 Infection Before and After Immunization with AstraZeneca Chadox1 in Mice.Current issues in molecular biology · 2025Article
- USP8 promotes intracellular infection by enhancing ESCRT-mediated membrane repair, limiting xenophagy, and reducing oxidative stress.Autophagy · 2025Article
- Insights into the protein ubiquitinome in the host‒pathogen interplay duringFrontiers in molecular biosciences · 2025Article
- Rheumatic diseases and latent tuberculosis infection in children: diagnostic and therapeutic challenges.Frontiers in cellular and infection microbiology · 2025Review
- Mycobacterium tuberculosis protein Rv2652c enhances intracellular survival by inhibiting host immune responses.Immunity, inflammation and disease · 2024Article
- Mycobacterium tuberculosis produces D-serine under hypoxia to limit CD8Nature microbiology · 2024Article
- Mycobacterium tuberculosis Rv1043c regulates the inflammatory response by inhibiting the phosphorylation of TAK1.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- E3 ubiquitin ligase CBLB regulates innate immune responses and bacterial dissemination during nontuberculous mycobacteria infection.Journal of leukocyte biology · 2024Article
- Mycobacterium tuberculosis suppresses host antimicrobial peptides by dehydrogenating L-alanine.Nature communications · 2024Article
- Live Attenuated Vaccines against Tuberculosis: Targeting the Disruption of Genes Encoding the Secretory Proteins of Mycobacteria.Vaccines · 2024Review
- Serine protease Rv2569c facilitates transmission of Mycobacterium tuberculosis via disrupting the epithelial barrier by cleaving E-cadherin.PLoS pathogens · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
20 authors at 3 institutions in 1 country.
Lin Wang *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Juehui Wu *Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Jun Li *Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Hua YangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Tianqi TangDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, China.
Haijiao LiangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Mianyong ZuoDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, China.
Jie WangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Haipeng LiuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Feng LiuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Jianxia ChenShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Zhonghua LiuShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yang WangDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, China.
Cheng PengDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, China.
Xiangyang WuDepartment of Microbiology and Immunology, Tongji University School of Medicine, Shanghai, China.
Ruijuan ZhengShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Xiaochen HuangShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China.
Yajun RanShanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, China.
Zihe RaoShanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, China. raozh@mail.tsinghua.edu.cn.
Baoxue GeShanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China. baoxue_ge@tongji.edu.cn.
Tongji University · CNShanghai Pulmonary Hospital · CNShanghaiTech University · CN
Funding
Howard Hughes Medical Institute
Abstract
Mycobacterium tuberculosis is an intracellular pathogen that uses several strategies to interfere with the signalling functions of host immune molecules. Many other bacterial pathogens exploit the host ubiquitination system to promote pathogenesis
Indexed as
UbiquitinationAnaphase-Promoting Complex-CyclosomeAnimalsApc2 Subunit, Anaphase-Promoting Complex-CyclosomeBacterial ProteinsCells, CulturedCytokinesFemaleHost-Pathogen InteractionsInflammation MediatorsLysineMacrophagesMiceMice, Inbred C57BLMycobacterium tuberculosisNF-kappa BANAPC2 protein, humanAnaphase-Promoting Complex-CyclosomeApc2 Subunit, Anaphase-Promoting Complex-CyclosomeBacterial ProteinsCytokinesInflammation MediatorsLysineNF-kappa BProtein Tyrosine Phosphatase, Non-Receptor Type 6TNF Receptor-Associated Factor 6Transcription Factor AP-1
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.