Evidence map›Paper›PMID 31941786›Full record

ArticleJournal of virology2020

Hemagglutinin and Neuraminidase Antibodies Are Induced in an Age- and Subtype-Dependent Manner after Influenza Virus Infection.

Sook-San Wong, Ben Waite, Jacqui Ralston, Tim Wood, G Edwin Reynolds, Ruth Seeds, E Claire Newbern, Mark G Thompson, Q Sue Huang, Richard J Webby and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

Sook-San WongState Key Laboratory of Respiratory Disease, Guangzhou Medical University, Guangzhou, People's Republic of China.
Ben WaiteInstitute of Environmental Science and Research, Ltd., NCBID-Wallaceville, Wallaceville, New Zealand.
Jacqui RalstonInstitute of Environmental Science and Research, Ltd., NCBID-Wallaceville, Wallaceville, New Zealand.
Tim WoodInstitute of Environmental Science and Research, Ltd., NCBID-Wallaceville, Wallaceville, New Zealand.
G Edwin ReynoldsImmunisation Advisory Centre (IMAC), University Services, University of Auckland, Auckland, New Zealand.
Ruth SeedsInstitute of Environmental Science and Research, Ltd., NCBID-Wallaceville, Wallaceville, New Zealand.
E Claire NewbernInstitute of Environmental Science and Research, Ltd., NCBID-Wallaceville, Wallaceville, New Zealand.
Mark G ThompsonInfluenza Division, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Q Sue HuangInstitute of Environmental Science and Research, Ltd., NCBID-Wallaceville, Wallaceville, New Zealand.
Richard J Webby
SHIVERS Investigation Team
New Zealand Institute for Public Health and Forensic Science · NZSt. Jude Children's Research Hospital · USCenters for Disease Control and Prevention · USUniversity of Auckland · NZ

Funding

NCIRD CDC HHS U01 IP000480NIAID NIH HHS HHSN266200700005CNIAID NIH HHS HHSN272201400006C
6 · The paper itself

Abstract

Despite evidence that antibodies targeting the influenza virus neuraminidase (NA) protein can be protective and are broadly cross-reactive, the immune response to NA during infection is poorly understood compared to the response to hemagglutinin (HA) protein. As such, we compared the antibody profile to HA and NA in two naturally infected human cohorts in Auckland, New Zealand: (i) a serosurvey cohort, consisting of pre- and post-influenza season sera from PCR-confirmed influenza cases (

Indexed as

AdolescentAdultAge FactorsAntibodies, ViralChildChild, PreschoolFemaleHemagglutinin Glycoproteins, Influenza VirusHumansImmunologic MemoryInfantInfant, NewbornInfluenza A virusInfluenza B virusInfluenza, HumanMaleAntibodies, ViralHemagglutinin Glycoproteins, Influenza VirusNeuraminidaseantibodyhemagglutination inhibitioninfluenzaneuraminidase inhibitionserology

Identifiers

PMID31941786
PMCPMC7081922
OpenAlexW2999320567

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.