Evidence map›Paper›PMID 31941722›Full record

ArticleMolecular cancer therapeutics2020

Extracellular Vesicle-Mediated

Alexis V Forterre, Jing-Hung Wang, Alain Delcayre, Kyuri Kim, Carol Green, Mark D Pegram, Stefanie S Jeffrey, A C Matin

Open access · bronzeAbstract read
In one paragraph

Article in Molecular cancer therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 58 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Applications of mRNA Delivery in Cancer Immunotherapy.International journal of nanomedicine · 2025
    Review
  8. Article
  9. mRNA-based therapeutic strategies for cancer treatment.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Alexis V ForterreDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California.
Jing-Hung WangDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California.
Alain DelcayreExoThera LLC, Menlo Park, California.
Kyuri KimSRI International, Menlo Park, California.
Carol GreenSRI International, Menlo Park, California.
Mark D PegramDepartment of Medicine, Stanford University School of Medicine, Stanford, California.ORCID 0000-0002-9743-8118
Stefanie S JeffreyDepartment of Surgery, Stanford University School of Medicine, Stanford, California.ORCID 0000-0003-4478-2764
A C MatinDepartment of Microbiology and Immunology, Stanford University School of Medicine, Stanford, California. a.matin@stanford.edu.ORCID 0000-0003-4468-980X
Stanford University · USSRI International · USStanford Medicine · USMeta (United States) · US

Funding

HER2-targeted exosomal delivery of therapeutic mRNA for enzyme pro-drug therapyUH3TR000902 · NCATS · STANFORD UNIVERSITY · PI MATIN, AC · 2016 to 2017
$2.0M
NCATS NIH HHS UH3 TR000902
6 · The paper itself

Abstract

Prodrugs are harmless until activated by a bacterial or viral gene product; they constitute the basis of gene-delivered prodrug therapies called GDEPT, which can kill tumors without major side effects. Previously, we utilized the prodrug CNOB (C

Indexed as

Genetic TherapyGene Transfer TechniquesAnimalsApoptosisBacterial ProteinsBreast NeoplasmsCell ProliferationErb-b2 Receptor Tyrosine KinasesExtracellular VesiclesFemaleHumansMiceMice, Inbred BALB CMice, NudeProdrugsRNA, MessengerBacterial ProteinsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesProdrugsRNA, Messenger

Identifiers

PMID31941722
PMCPMC7056535
OpenAlexW2999926188

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.