Evidence map›Paper›PMID 31941702›Full record

ArticleBiology open2020

Leucine-rich repeat containing 8A contributes to the expansion of brain ventricles in zebrafish embryos.

Yen-Tzu Tseng, Chun-Lin Ko, Chia-Teng Chang, Yen-Hua Lee, Wei-Chun Huang Fu, I-Hsuan Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yen-Tzu TsengDepartment of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan.
Chun-Lin KoDepartment of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan.
Chia-Teng ChangDepartment of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan.
Yen-Hua LeeDepartment of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan.
Wei-Chun Huang FuGraduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei, 110 Taiwan.
I-Hsuan LiuDepartment of Animal Science and Technology, National Taiwan University, Taipei, 106, Taiwan ihliu@ntu.edu.tw.ORCID http://orcid.org/0000-0002-4524-3263
National Taiwan University of Science and Technology · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sodium osmotic gradient is necessary for the initiation of brain ventricle inflation, but a previous study predicted that organic and inorganic osmolytes play equivalently important roles in osmotic homeostasis in astrocytes. To test whether organic osmoregulation also plays a role in brain ventricle inflation, the core component for volume-regulated anion and organic osmolyte channel,

Indexed as

BrainEmbryo, NonmammalianGene Expression Regulation, DevelopmentalIon ChannelsZebrafishZebrafish ProteinsAnimalsAstrocytesOsmoregulationIon ChannelsZebrafish ProteinsLrrc8AOrganic osmoregulationTaurineVolume-regulated anion channel (VRAC)Volume-sensitive organic osmolyte/anion channel (VSOAC)

Identifiers

PMID31941702
PMCPMC6994961
OpenAlexW3000012981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.