Evidence map›Paper›PMID 31941492›Full record

ArticleAnnals of clinical microbiology and antimicrobials2020

Molecular epidemiology and antimicrobial resistance features of Acinetobacter baumannii clinical isolates from Pakistan.

Nabil Karah, Fizza Khalid, Sun Nyunt Wai, Bernt Eric Uhlin, Irfan Ahmad

Open access · goldAbstract read
In one paragraph

Article in Annals of clinical microbiology and antimicrobials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
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  13. Molecular characterization of multidrug resistantFrontiers in cellular and infection microbiology · 2023
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  14. Diversity of carbapenem-resistantMicrobial genomics · 2022
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  16. A Comprehensive Study of the Relationship between the Production ofInternational journal of microbiology · 2021
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  17. Molecular Epidemiology of Extensively-Drug ResistantInfection and drug resistance · 2021
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  18. What do we know about plasmids carried by members of the Acinetobacter genus?World journal of microbiology & biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Nabil KarahThe Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, and Umea Centre for Microbial Research, Umea University, Umeå, Sweden. nabil.karah@umu.se.ORCID http://orcid.org/0000-0001-8867-658X
Fizza KhalidDepartment of Microbiology, University of Health Sciences, Lahore, Pakistan.
Sun Nyunt WaiThe Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, and Umea Centre for Microbial Research, Umea University, Umeå, Sweden.
Bernt Eric UhlinThe Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, and Umea Centre for Microbial Research, Umea University, Umeå, Sweden.
Irfan AhmadThe Laboratory for Molecular Infection Medicine Sweden, Department of Molecular Biology, and Umea Centre for Microbial Research, Umea University, Umeå, Sweden. irfan.ahmad@uhs.edu.pk.
Umeå University · SEUniversity of Health Sciences Lahore · PK

Funding

HEC Pakistan Grant 8666/Punjab/NRPU/2017Kempe Foundations grants JCK-1527Kempe Foundations JCK-1724Swedish Research Council 2015-06824Swedish Research Council 2018-02914Swedish Research Council grants 2015-03007
6 · The paper itself

Abstract

backgroundAcinetobacter baumannii is a Gram-negative opportunistic pathogen with a notorious reputation of being resistant to antimicrobial agents. The capability of A. baumannii to persist and disseminate between healthcare settings has raised a major concern worldwide.

methodsOur study investigated the antibiotic resistance features and molecular epidemiology of 52 clinical isolates of A. baumannii collected in Pakistan between 2013 and 2015. Antimicrobial susceptibility patterns were determined by the agar disc diffusion method. Comparative sequence analyses of the ampC and bla

resultsOverall, the isolates were grouped into 7 clusters and 3 sporadic isolates. The largest cluster, Ab-Pak-cluster-1 (bla

conclusionsOur study detected the occurrence of 7 clusters of A. baumannii in Pakistan. Altogether, 6/7 of the clusters and 45/52 (86.5%) of the isolates belonged to IC I (n = 9) or II (n = 36), making Pakistan no exception to the global domination of these two clones. The onset of ST158 in Pakistan marked a geographical dispersal of this clone beyond the Middle East and brought up the need for a detailed characterization.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsMolecular EpidemiologyAnti-Bacterial AgentsBacterial ProteinsCross InfectionDrug Resistance, BacterialGenome, BacterialHumansMicrobial Sensitivity TestsOpportunistic InfectionsPakistanPhylogenyAnti-Bacterial AgentsBacterial ProteinsCarbapenem-resistanceInternational clonePhylogenyStrain typing

Identifiers

PMID31941492
PMCPMC6964048
OpenAlexW3001832021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.