ArticleBMC psychiatry2020
Mediation and moderation analyses: exploring the complex pathways between hope and quality of life among patients with schizophrenia.
Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Trial
- Family cumulative risk and meaning in life among Chinese secondary vocational school students: the mediating role of self-esteem and the moderating role of labor education support perception.Frontiers in psychology · 2026Article
- Application of a cognitive-structure framework-based scenario-based education programme in schizophrenia patients with delusional symptoms: a randomised controlled trial.Frontiers in psychiatry · 2026Article
- The mediating role of spiritual well-being in the relationship between self-care agency and hope in patients diagnosed with schizophrenia: a cross-sectional and correlational study.BMC psychiatry · 2025Article
- Article
- Relationship between medication burden and medication experience in stable patients with schizophrenia: the mediating effect of medication belief.BMC nursing · 2024Article
- Construction and verification of aggressive behavior risk prediction model in stable patients with schizophrenia.BMC psychiatry · 2023Article
- Correction to: Mediation and moderation analyses: exploring the complex pathways between hope and quality of life among patients with schizophrenia.BMC psychiatry · 2021Article
- A cross-sectional study addressing the importance of work and other everyday activities for well-being among people with mental illness: does additional vulnerability matter?BMC psychiatry · 2021Article
- Mediating Effect of Hope on the Relationship Between Depression and Recovery in Persons With Schizophrenia.Frontiers in psychiatry · 2021Article
- Type C Behavior and Associated Factors in Patients with Breast Cancer During Postoperative Chemotherapy: A Cross-Sectional Study.Psychology research and behavior management · 2021Article
- Resilience and Related Factors: A Comparison of Fathers and Mothers of Patients With Cleft Lip and/or Palate in China.Frontiers in psychiatry · 2021Article
- The Mediating Role of Hope in the Relationship Between Perceived Stress and Post-Traumatic Stress Disorder Among Chinese Patients with Oral Cancer: A Cross-Sectional Study.Cancer management and research · 2021Article
- Prevalence and predictors of anxiety and depressive symptoms among patients diagnosed with oral cancer in China: a cross-sectional study.BMC psychiatry · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
backgroundThe underlying mechanism between hope and quality of life is as yet unknown. We aim to examine the potential mediating effect of depression and resilience and the moderated effect of sex in this well-established association.
methodsTwo hundred seven patients diagnosed with schizophrenia were administered a questionnaire battery that measured hope, depression, resilience and QOL. A multiple mediation model was used to examine the mediating effect of resilience and depression on the association between hope and QOL. A subgroup analysis was performed and a moderated mediation model was examined to find and test the moderated effect of sex on the mediation model. We used Mplus to perform moderation and mediation analyses so that the mediators and moderator could function together in the same model.
resultSex was the moderator on the direct path between hope and QOL. The relationship between hope and QOL was mediated by resilience and depression in both sexes. When compared with female patients, the effect of hope on QOL was completely mediated by resilience and depression in males. In female patients, the model was partially mediated, and the direct effect of hope on QOL was significantly negatively correlated with the level of hope.
conclusionWe present a conceptual model containing the mediated effects of resilience and depression and the moderated effect of sex between hope and QOL, which we believe facilitates the understanding of these associations. This model should be useful in the formulation of strategies to improve QOL.
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