Evidence map›Paper›PMID 31941457›Full record

ArticleBMC gastroenterology2020

Liver injury monitoring, fibrosis staging and inflammation grading using T1rho magnetic resonance imaging: an experimental study in rats with carbon tetrachloride intoxication.

Shuangshuang Xie, Hanxiong Qi, Qing Li, Kun Zhang, Longjiang Zhang, Yue Cheng, Wen Shen

Abstract read
In one paragraph

Article in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shuangshuang XieDepartment of Radiology, First Central Hospital Clinical Institute, Tianjin Medical University, 22 Qixiangtai Road, Heping District, Tianjin, 300070, China.
Hanxiong QiDepartment of Radiology, Tianjin First Central Hospital, Tianjin medical imaging institute, 24 Fukang Road, Nankai District, Tianjin, 300192, China.
Qing LiDepartment of Radiology, Tianjin First Central Hospital, Tianjin medical imaging institute, 24 Fukang Road, Nankai District, Tianjin, 300192, China.
Kun ZhangDepartment of Radiology, Tianjin First Central Hospital, Tianjin medical imaging institute, 24 Fukang Road, Nankai District, Tianjin, 300192, China.
Longjiang ZhangDepartment of Medical Imaging, Jinling Hospital, Medical School of Nanjing University, 305 Zhongshan East Road, Nanjing, 210002, Jiangsu, China.
Yue ChengDepartment of Radiology, Tianjin First Central Hospital, Tianjin medical imaging institute, 24 Fukang Road, Nankai District, Tianjin, 300192, China.
Wen ShenDepartment of Radiology, Tianjin First Central Hospital, Tianjin medical imaging institute, 24 Fukang Road, Nankai District, Tianjin, 300192, China. shenwen66happy@126.com.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China (CN) 81873888National Natural Science Foundation of China 81671657National Natural Science Fund of China 81901710
6 · The paper itself

Abstract

backgroundTo investigate the merit of T1rho relaxation for the evaluation of liver fibrosis, inflammatory activity, and liver injury monitoring in a carbon tetrachloride (CCl

methodsModel rats from CCl

resultsIn the fibrosis group, liver T1rho values increased gradually within week 8 and then decreased. In the regression group, T1rho values dropped gradually after the withdrawal of CCl

conclusionT1rho MRI can be used to monitor CCl

Indexed as

AnimalsCarbon TetrachlorideDisease Models, AnimalImage Processing, Computer-AssistedInflammationLiverLiver CirrhosisMagnetic Resonance ImagingRatsCarbon TetrachlorideInflammation activityLiver fibrosisT1rho magnetic resonance imaging

Identifiers

PMID31941457
PMCPMC6964054

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.