Observational studyBMC nephrology2020
Definition of hourly urine output influences reported incidence and staging of acute kidney injury.
Observational study in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Controversies in acute kidney injury: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Conference.Kidney international · 2020 · on this mapGuideline
- The effect of normothermic machine perfusion on acute kidney injury following liver transplantation: a propensity score-matched, retrospective, single-centre, cohort study.EClinicalMedicine · 2026Article
- Association between serum glucose/potassium ratio and acute kidney injury in patients with traumatic brain injury: based on MIMIC-IV database.Journal of global health · 2026Article
- Machine learning prediction of moderate-to-severe acute kidney injury after ICU admission and cardiac surgery with urine trace elements.European journal of clinical investigation · 2026Article
- A prospective diagnostic study investigating urinary biomarkers of AKI in major abdominal surgery (the AKI-biomas study).Critical care (London, England) · 2025Observational
- Toward the standardization of big datasets of urine output for AKI analysis: a multicenter validation study.Scientific reports · 2025Article
- Short- and long-term outcomes in oliguric and non-oliguric acute kidney injury in intensive care: a retrospective, post hoc, bicentric study.Clinical kidney journal · 2025Article
- Temporary bilateral clamping of renal arteries induces ischemia-reperfusion: A new pig model of acute kidney injury using total intravenous anesthesia.Physiological reports · 2025Article
- Machine learning approaches toward an understanding of acute kidney injury: current trends and future directions.The Korean journal of internal medicine · 2024Review
- Association between hyperglycemia at ICU admission and postoperative acute kidney injury in patients undergoing cardiac surgery: Analysis of the MIMIC-IV database.Journal of intensive medicine · 2024Article
- Averaged versus Persistent Reduction in Urine Output to Define Oliguria in Critically Ill Patients: An Observational Study.Clinical journal of the American Society of Nephrology : CJASN · 2024Article
- Urine output is an early and strong predictor of acute kidney injury and associated mortality: a systematic literature review of 50 clinical studies.Annals of intensive care · 2024Review
- Early Sepsis-Associated Acute Kidney Injury and Obesity.JAMA network open · 2024Article
- Identification of an optimal threshold to define oliguria in critically ill patients: an observational study.Critical care (London, England) · 2023Observational
- Efficacy of orally administered montmorillonite in myoglobinuric acute renal failure model in male rats.Iranian journal of basic medical sciences · 2023Article
- Improving awareness of kidney function through electronic urine output monitoring: a comparative study.BMC nephrology · 2022Article
- External validation of a deep-learning model to predict severe acute kidney injury based on urine output changes in critically ill patients.Journal of nephrology · 2022Article
- Effect of water diuresis with hydrogen saturation on the course of acute kidney damage during the separation of oxidation and phosphorylation.Journal of medicine and life · 2022Article
- Impact of Different KDIGO Criteria on Clinical Outcomes for Early Identification of Acute Kidney Injury after Non-Cardiac Surgery.Journal of clinical medicine · 2022Article
- Urinary Trace Elements Are Biomarkers for Early Detection of Acute Kidney Injury.Kidney international reports · 2022Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
backgroundAcute kidney injury (AKI) is commonly defined using the KDIGO system, which includes criteria based on reduced urine output (UO). There is no consensus on whether UO should be measured using consecutive hourly readings or mean output. This makes KDIGO UO definition and staging of AKI vulnerable to inconsistency which has implications both for research and clinical practice. The objective of this study was to investigate whether the way in which UO is defined affects incidence and staging of AKI.
methodsWe conducted a retrospective analysis of two single centre observational studies investigating (i) patients undergoing cardiac surgery and (ii) patients admitted to general intensive care units (ICU). AKI was identified using KDIGO serum creatinine (SCr) criteria and two methods of UO (UO
resultsData from 151 CICU and 150 ICU admissions were analysed. Incidence of AKI using SCr alone was 23.8% in CICU and 32% in ICU. Incidence increased in both groups when UO was considered, with inclusion of UO
conclusionsWe demonstrate a serious lack of clarity in the internationally accepted AKI definition leading to significant variability in reporting of AKI incidence.
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