Evidence map›Paper›PMID 31940969›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Current Status of PSMA-Radiotracers for Prostate Cancer: Data Analysis of Prospective Trials Listed on ClinicalTrials.gov.

Claus Zippel, Sarah C Ronski, Sabine Bohnet-Joschko, Frederik L Giesel, Klaus Kopka

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Contrast media & molecular imaging · 2021
    Pooled it
  2. Pooled it
  3. Imaging the hallmarks of cancer.Nature reviews. Cancer · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Diagnostic value of integratedProstate international · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Risk of metastatic disease using [EJNMMI research · 2021
    Article
  17. Review
  18. On site production of [EJNMMI radiopharmacy and chemistry · 2021
    Article
  19. Rise of Clinical Studies in the Field of Machine Learning: A Review of Data Registered in ClinicalTrials.gov.International journal of environmental research and public health · 2021
    Review
  20. Diagnostic Role ofDiagnostics (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claus ZippelFaculty of Management and Economics, Witten/Herdecke University, 58448 Witten, Germany.
Sarah C RonskiPraxis für Nuklearmedizin, Klinikum der Stadt Ludwigshafen, 67063 Ludwigshafen am Rhein, Germany.
Sabine Bohnet-JoschkoFaculty of Management and Economics, Witten/Herdecke University, 58448 Witten, Germany.ORCID 0000-0002-1119-9786
Frederik L GieselDepartment of Nuclear Medicine, Heidelberg University Hospital, 69120 Heidelberg, Germany.
Klaus KopkaHelmholtz-Zentrum Dresden-Rossendorf (HZDR), Institute of Radiopharmaceutical Cancer Research, 01328 Dresden, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recent development of dedicated prostate-specific membrane antigen (PSMA) targeted radioligands shows the potential to change and improve the diagnosis and therapy of prostate cancer. There is an increasing number of prospective trials to further establish these tracers in the clinical setting. We analyzed data from the ClinicalTrials.gov registry including all listed prospective trials with PSMA-ligands for prostate cancer as of October 2019 concerning the different tracers and study characteristics. We found

Indexed as

ClinicalTrials.govprostate cancerPSMA tracerregistry data analysistheranostics

Identifiers

PMID31940969
PMCPMC7168903

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.