Evidence map›Paper›PMID 31940913›Full record

ArticleMolecules (Basel, Switzerland)2020

The Synthesis and Functional Study of Multicolor Nitrogen-Doped Carbon Dots for Live Cell Nuclear Imaging.

Yanan Zhang, Xingwei Zhang, Yanping Shi, Chao Sun, Nan Zhou, Haixia Wen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Recent Advances in Carbon Dots forFrontiers in chemistry · 2022
    Review
  6. Article
  7. A Review of Carbon Dots Produced from Biomass Wastes.Nanomaterials (Basel, Switzerland) · 2020
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yanan ZhangDepartment of Physiology, Harbin Medical University, Harbin 150081, China.
Xingwei ZhangDepartment of Chemistry, Northeast Agricultural University, Harbin 150025, China.
Yanping ShiDepartment of Chemistry, Northeast Agricultural University, Harbin 150025, China.
Chao SunDepartment of Chemistry, Northeast Agricultural University, Harbin 150025, China.
Nan ZhouDepartment of Chemistry, Northeast Agricultural University, Harbin 150025, China.ORCID 0000-0001-7104-8886
Haixia WenDepartment of Physiology, Harbin Medical University, Harbin 150081, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nitrogen-doped carbon dots (N-CQDs) were synthesized by citric acid as a raw material and propylene diamine as a passivation agent. Structure, optical properties and biocompatibility of N-CQDs were analyzed. It was found that the N-CQDs possessed concentration-dependent, multicolor photoluminescence and low toxicity. As demonstrated in the imaging of bioluminescence, by adjusting the concentration of N-CQDs, the cell imaging effect can be adjusted. The internalized N-CQDs were concentrated in the nucleus. A novel tool for studying the nuclear changes during the cell cycle was developed.

Indexed as

Biological TransportCarbonCell Line, TumorCell NucleusCell SurvivalCitric AcidDiaminesFluorescent DyesHeLa CellsHumansMicroscopy, FluorescenceQuantum DotsCarbonCitric AcidDiaminesFluorescent Dyesmitosismulticolor cell nuclear imagingmulticolor illuminationnitrogen-doped carbon dots

Identifiers

PMID31940913
PMCPMC7024153

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.