ArticleSensors (Basel, Switzerland)2020
Demonstration of Optical Coherence Tomography Guided Big Bubble Technique for Deep Anterior Lamellar Keratoplasty (DALK).
Article in Sensors (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Head-mounted surgical robots are an enabling technology for subretinal injections.Science robotics · 2025Article
- High-resolutionBiomedical optics express · 2024Article
- Design and Evaluation of an Eye Mountable AutoDALK Robot for Deep Anterior Lamellar Keratoplasty.Micromachines · 2024Article
- Automatic and real-time tissue sensing for autonomous intestinal anastomosis using hybrid MLP-DC-CNN classifier-based optical coherence tomography.Biomedical optics express · 2024Article
- Eye-mounting goggles to bridge the gap between benchtop experiments and in vivo robotic eye surgery.Scientific reports · 2023Article
- Common-path optical coherence tomography guided vertical pneumodissection for DALK.Proceedings of SPIE--the International Society for Optical Engineering · 2023Article
- Ex Vivo Evaluation of a Pressure-Sensitive Device to Aid Big Bubble Intrastromal Dissection in Deep Anterior Lamellar Keratoplasty.Translational vision science & technology · 2022Article
- Optical coherence tomography refraction and optical path length correction for image-guided corneal surgery.Biomedical optics express · 2022Article
- Convolutional neural network-based common-path optical coherence tomography A-scan boundary-tracking training and validation using a parallel Monte Carlo synthetic dataset.Optics express · 2022Article
- Higher-order regression three-dimensional motion-compensation method for real-time optical coherence tomography volumetric imaging of the cornea.Journal of biomedical optics · 2022Article
- Data-Driven Modelling and Control for Robot Needle Insertion in Deep Anterior Lamellar Keratoplasty.IEEE robotics and automation letters · 2022Article
- Convolutional Neural Network-based Optical Coherence Tomography (OCT) A-scan Segmentation and Tracking Platform using Advanced Monte Carlo Simulation.Biomedical optics (Washington, D.C.) · 2021Article
- Downward viewing common-path optical coherence tomography guided hydro-dissection needle for DALK.Proceedings of SPIE--the International Society for Optical EngineeringArticle
- Head-Mounting Surgical Robots for Passive Compensation of Patient Motion.Journal of medical robotics researchArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Deep anterior lamellar keratoplasty (DALK) is a highly challenging procedure for cornea transplant that involves removing the corneal layers above Descemet's membrane (DM). This is achieved by a "big bubble" technique where a needle is inserted into the stroma of the cornea down to DM and the injection of either air or liquid. DALK has important advantages over penetrating keratoplasty (PK) including lower rejection rate, less endothelial cell loss, and increased graft survival. In this paper, we successfully designed and evaluated the optical coherence tomography (OCT) distal sensor integrated needle for a precise big bubble technique. We successfully used this sensor for micro-control of a robotic DALK device termed AUTO-DALK for autonomous big bubble needle insertion. The OCT distal sensor was integrated inside a 25-gauge needle, which was used for pneumo-dissection. The AUTO-DALK device is built on a manual trephine platform which includes a vacuum ring to fix the device on the eye and add a needle driver at an angle of 60 degrees from vertical. During the test on five porcine eyes with a target depth of 90%, the measured insertion depth as a percentage of cornea thickness for the AUTO-DALK device was 90 . 05 % ± 2 . 33 % without any perforation compared to 79 . 16 % ± 5 . 68 % for unassisted free-hand insertion and 86 . 20 % ± 5 . 31 % for assisted free-hand insertion. The result showed a higher precision and consistency of the needle placement with AUTO-DALK, which could lead to better visual outcomes and fewer complications.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.