ArticleThe Journal of allergy and clinical immunology2020
Food aversion and poor weight gain in food protein-induced enterocolitis syndrome: A retrospective study.
Article in The Journal of allergy and clinical immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.
- A Systematic Review of Food Protein-Induced Enterocolitis Syndrome.International archives of allergy and immunology · 2023Pooled it
- Risk factors for severe reactions in food allergy: Rapid evidence review with meta-analysis.Allergy · 2022Pooled it
- Fear and picky eating-related ARFID behaviors in children with food allergy.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026Article
- Food protein-induced enterocolitis syndrome: Disease burden for patients and families.Journal of food allergy · 2025Review
- Clinical Significance of Egg Sensitization in Pediatric Food Protein-Induced Enterocolitis Syndrome to Hen's Egg.The journal of allergy and clinical immunology. In practice · 2025Article
- Food Protein-Induced Enterocolitis Syndrome Across Lifespan: Focus on Adolescence.Journal of clinical medicine · 2025Review
- Neonatal Food Protein-Induced Enterocolitis: Current Insights and Knowledge Gaps.Journal of clinical medicine · 2025Review
- Food protein-induced enterocolitis syndrome (FPIES) following COVID-19 infection: a case report.Frontiers in allergy · 2025Article
- Non-immunoglobulin E-mediated food allergy.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024Review
- Adverse Food Reactions: Physiological and Ecological Perspectives.Annual review of nutrition · 2024Review
- Piloting a multidisciplinary group education session to support caregivers of children with food protein-induced enterocolitis syndrome (FPIES).The journal of allergy and clinical immunology. In practice · 2023Article
- Early infancy dysbiosis in food protein-induced enterocolitis syndrome: A prospective cohort study.Allergy · 2023Article
- Food protein-induced enterocolitis syndrome: Healthcare utilization and referral patterns among a pediatric cohort.Frontiers in allergy · 2023Article
- Perspectives on Non-IgE-Mediated Gastrointestinal Food Allergy in Pediatrics: A Review of Current Evidence and Guidelines.Journal of asthma and allergy · 2023Review
- Recent Update in Food Protein-Induced Enterocolitis Syndrome: Pathophysiology, Diagnosis, and Management.Allergy, asthma & immunology research · 2022Review
- Update on Food Protein-Induced Enterocolitis Syndrome (FPIES).Current allergy and asthma reports · 2022Review
- Adherence to dietary prescriptions in patients with acute food protein-induced enterocolitis syndrome.Pediatric investigation · 2022Article
- Food protein-induced enterocolitis syndrome: A large French multicentric experience.Clinical and translational allergy · 2022Article
- The evolution of food protein-induced enterocolitis syndrome: From a diagnosis that did not exist to a condition in need of answers.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2021Review
- Review
Corrections and comments
- Erratum issuedCorrigendum.2020
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundFood protein-induced enterocolitis syndrome (FPIES) is a form of non-IgE-mediated gastrointestinal food allergy. Insufficient data exist in regard to gastrointestinal history and outcome, particularly comorbidity, family history, food aversion, and poor body weight gain.
objectiveWe sought to identify the gastrointestinal outcomes and related risk factors in FPIES.
methodsWe analyzed the clinical features and gastrointestinal outcomes of patients with FPIES retrospectively at 4 hospitals in Boston.
resultsTwo hundred three patients with FPIES were identified, including 180 only with acute FPIES, 8 with chronic FPIES, and 15 with both. Oat (34.5%), rice (29.6%), and cow's milk (19.2%) were the most common food triggers. The prevalence rates of personal history with allergic proctocolitis (23.2%) and family history with inflammatory bowel diseases (9.4%) and celiac disease (7.3%) were higher than those in the general population. Compared with patients with FPIES with 1 or 2 food triggers, the risk of developing food aversion increased in cases triggered by 3 or more foods (adjusted odds ratio, 3.07; 95% CI, 1.38-6.82; P = .006). The risk of poor body weight gain increased in FPIES triggered by cow's milk (adjusted odds ratio, 3.41; 95% CI, 1.21-9.63; P = .02) and banana (adjusted odds ratio, 7.63; 95% CI, 2.10-27.80; P = .002).
conclusionsGastrointestinal comorbidities and family history were common in patients with FPIES. Patients with FPIES with 3 or more triggers were at risk of food aversion. Patients with FPIES with cow's milk and banana as triggers were at risk of poor body weight gain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.