Evidence map›Paper›PMID 31940271›Full record

ArticleImmunity2020

Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.

Scott A Jenks, Kevin S Cashman, Esther Zumaquero, Urko M Marigorta, Aakash V Patel, Xiaoqian Wang, Deepak Tomar, Matthew C Woodruff, Zoe Simon, Regina Bugrovsky and 13 more

Abstract readPublished Erratum
In one paragraph

Article in Immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
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  14. Atypical and non-classical CD45RBNature communications · 2024
    Article
  15. Article
  16. Article
  17. Review
  18. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Scott A Jenks
Kevin S Cashman
Esther Zumaquero
Urko M Marigorta
Aakash V Patel
Xiaoqian Wang
Deepak Tomar
Matthew C Woodruff
Zoe Simon
Regina Bugrovsky
Emily L Blalock
Christopher D Scharer
Christopher M Tipton
Chungwen Wei
S Sam Lim
Michelle Petri
Timothy B Niewold
Jennifer H Anolik
Greg Gibson
F Eun-Hyung Lee
Jeremy M Boss
Frances E Lund
Ignacio Sanz

Funding

Regulation of B cell Responses in SLE and Other Autoimmune DiseasesU19AI110483 · NIAID · EMORY UNIVERSITY · PI JEREMY M. BOSS · 2014 to 2026
$76.6M
Regulation of Pathogenic Plasma Cells in Human SLEP01AI125180 · NIAID · EMORY UNIVERSITY · PI Ignacio E. Sanz · 2016 to 2026
$28.2M
Role of B Cells in Synovial Inflammation & LN Remodeling in RA ArthritisP01AI078907 · NIAID · UNIVERSITY OF ROCHESTER · PI LOONEY, RICHARD JOHN · 2010 to 2014
$10.8M
PREDOCTORAL TRAINING PROGRAM IN GENETICST32GM008490 · NIGMS · EMORY UNIVERSITY · PI BOSS, JEREMY M. · 1993 to 2022
$8.0M
A Model System for the Study of Human B-cell ToleranceR37AI049660 · NIAID · UNIVERSITY OF ROCHESTER · PI SANZ, IGNACIO E. · 2010 to 2019
$3.7M
IMMUNE FUNCTION AND BIODEFENSE IN CHILDREN. ELDERLY AND IMMUNOCOMPROMI-266050029N01AI050029 · NIAID · UNIVERSITY OF ROCHESTER · PI SANZ, IGNACIO E. · 2006 to 2006
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NIAID NIH HHS N01 AI050029NIAID NIH HHS P01 AI078907NIAID NIH HHS P01 AI125180NIAID NIH HHS R37 AI049660NIAID NIH HHS U19 AI110483NIGMS NIH HHS T32 GM008490
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID31940271
PMCPMC6993874

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.