Evidence map›Paper›PMID 31940244›Full record

ArticleCirculation. Arrhythmia and electrophysiology2020

Association of Left Atrial High-Resolution Late Gadolinium Enhancement on Cardiac Magnetic Resonance With Electrogram Abnormalities Beyond Voltage in Patients With Atrial Fibrillation.

Ling Kuo, Erica Zado, David Frankel, Pasquale Santangeli, Jeffrey Arkles, Yuchi Han, Francis E Marchlinski, Saman Nazarian, Benoit Desjardins

Erratum issuedAbstract read
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. SCMR expert consensus statement for cardiovascular magnetic resonance of patients with a cardiac implantable electronic device.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
    Guideline
  2. Article
  3. Article
  4. Review
  5. Article
  6. Autonomic modulation impacts conduction velocity dynamics and wavefront propagation in the left atrium.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  7. Left atrial volume affects the correlation of voltage map with magnetic resonance imaging.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2024
    Article
  8. Article
  9. Article
  10. All That Glitters Is Not Scar.Circulation. Arrhythmia and electrophysiology · 2022
    Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Ling KuoDivision of Cardiology, Department of Medicine, Taipei Veterans General Hospital, Taiwan (L.K.).
Erica ZadoElectrophysiology Section, Cardiovascular Division, Department of Medicine (L.K., E.Z., D.F., P.S., J.A., F.E.M., S.N.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
David FrankelElectrophysiology Section, Cardiovascular Division, Department of Medicine (L.K., E.Z., D.F., P.S., J.A., F.E.M., S.N.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Pasquale SantangeliElectrophysiology Section, Cardiovascular Division, Department of Medicine (L.K., E.Z., D.F., P.S., J.A., F.E.M., S.N.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Jeffrey ArklesElectrophysiology Section, Cardiovascular Division, Department of Medicine (L.K., E.Z., D.F., P.S., J.A., F.E.M., S.N.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Yuchi HanCardiovascular Division, Department of Medicine (Y.H.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Francis E MarchlinskiElectrophysiology Section, Cardiovascular Division, Department of Medicine (L.K., E.Z., D.F., P.S., J.A., F.E.M., S.N.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Saman NazarianElectrophysiology Section, Cardiovascular Division, Department of Medicine (L.K., E.Z., D.F., P.S., J.A., F.E.M., S.N.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Benoit DesjardinsCardiovascular Imaging Section, Department of Radiology (B.D), Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

Funding

Implications of Intra-Myocardial Fat Deposition upon Propensity for Malignant ArrhythmiaR01HL142893 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI NAZARIAN, SAMAN, TRAYANOVA, NATALIA A. · 2018 to 2021
$2.5M
ANCILLARY STUDY OF SUBSTRATE AND INTERVENTION MECHANISMS FOR MALIGNANT ARRHYTHMIAR01HL116280 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI NAZARIAN, SAMAN · 2013 to 2016
$1.2M
NHLBI NIH HHS R01 HL116280NHLBI NIH HHS R01 HL142893
6 · The paper itself

Abstract

backgroundConflicting data have been reported on the association of left atrial (LA) late gadolinium enhancement (LGE) with atrial voltage in patients with atrial fibrillation. The association of LGE with electrogram fractionation and delay remains to be examined. We sought to examine the association between LA LGE on cardiac magnetic resonance and electrogram abnormalities in patients with atrial fibrillation.

methodsHigh-resolution LGE cardiac magnetic resonance was performed before electrogram mapping and ablation in atrial fibrillation patients. Cardiac magnetic resonance features were quantified using LA myocardial signal intensity

resultsIn the 40 patients with atrial fibrillation (age, 63.2±9.2 years; 1312.3±767.3 electrogram points per patient), lower bipolar voltage was associated with higher SI-Z in patients who had undergone previous ablation (coefficient, -0.049;

conclusionsThe association of LA LGE with voltage is modified by ablation. Importantly, in ablation-naive patients, atrial LGE is associated with electrogram fractionation even in the absence of voltage abnormalities.

Indexed as

ElectrocardiographyAtrial FibrillationCatheter AblationContrast MediaEpicardial MappingFemaleHumansImaging, Three-DimensionalMagnetic Resonance AngiographyMaleMeglumineMiddle AgedOrganometallic CompoundsProspective StudiesContrast Mediagadoterate meglumineMeglumineOrganometallic Compoundsatrial fibrillationheart atriahumansmagnetic resonance imagingmyocardium

Identifiers

PMID31940244
PMCPMC7031051

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.