Evidence map›Paper›PMID 31940220›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2020

Genetic variability of T cell responses in hypersensitivity pneumonitis identified using the BXD genetic reference panel.

Jin Wang, Tae Won Yoon, Robert Read, Ae-Kyung Yi, Robert W Williams, Elizabeth A Fitzpatrick

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jin WangIntegrated Biomedical Science Graduate Program, College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, Tennessee.
Tae Won YoonIntegrated Biomedical Science Graduate Program, College of Graduate Health Sciences, University of Tennessee Health Science Center, Memphis, Tennessee.
Robert ReadDepartment of Biological Sciences, University of Memphis, Memphis, Tennessee.
Ae-Kyung YiDepartment of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.
Robert W WilliamsDepartment of Biological Sciences, University of Memphis, Memphis, Tennessee.
Elizabeth A FitzpatrickDepartment of Microbiology, Immunology, and Biochemistry, College of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee.
University of Tennessee Health Science Center · USUniversity of Memphis · US

Funding

TLR/IL-1R signaling intermediaries and a target-specific therapeutic for arthritiR01AR064723 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI YI, AE-KYUNG · 2014 to 2018
$1.6M
NIAMS NIH HHS R01 AR064723
6 · The paper itself

Abstract

Hypersensitivity pneumonitis (HP) is an interstitial lung disease that may progress to fibrosis and significant risk of death. HP develops following repeated exposures to inhaled environmental antigens; however, only a fraction of the exposed population develops the disease, suggesting that host genetics contribute to disease susceptibility. We used the BXD family of mice with the

Indexed as

Alveolitis, Extrinsic AllergicAnimalsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesEpithelial-Mesenchymal TransitionFemaleGenetic VariationLungMaleMiceMice, Inbred C57BLMice, Inbred DBANeutrophilsSaccharopolysporaUp-Regulationfibrosisforward geneticsgenetic susceptibilityQTLT cells

Identifiers

PMID31940220
PMCPMC7191482
OpenAlexW2999689375

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.