ReviewCurrent cardiology reports2020
Diagnosis and Management of Tuberculous Pericarditis: What Is New?
Review in Current cardiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Tuberculous Pericarditis in Childhood: A Case Report and a Systematic Literature Review.Pathogens (Basel, Switzerland) · 2024Pooled it
- Diagnostic accuracy of the Xpert MTB/RIF assay for tuberculous pericarditis: A systematic review and meta-analysis.PloS one · 2021Pooled it
- Diagnostic performance of third-generation sequencing for tuberculous pericarditis: a systematic review and meta-analysis protocol.BMJ open · 2026Article
- ECMO-Supported Pericardiectomy in Constrictive Tuberculous Pericarditis With Severe Ventricular Dysfunction.JACC. Case reports · 2026Article
- MELD 3.0 Score and Time to Discharge After Pericardiectomy: A Competing Risks Analysis in Tuberculous Constrictive Pericarditis.Journal of clinical medicine · 2026Article
- Pericardial calcification in tuberculous constrictive pericarditis: a marker of chronicity unassociated with early postoperative outcomes.Quantitative imaging in medicine and surgery · 2026Article
- Subacute respiratory symptoms in a patient with Crohn's disease and ankylosing spondylitis.The Korean journal of internal medicine · 2026Article
- A single-cell and spatial transcriptomic atlas of human tuberculous constrictive pericardium.EBioMedicine · 2026Article
- Fundamentals of Acute Pericarditis: State of the Art.Arquivos brasileiros de cardiologia · 2026Review
- Cardiovascular Complications from Tuberculosis.Reviews in cardiovascular medicine · 2025Review
- Clinical Characteristics and Outcomes of Patients with Constrictive Pericarditis Following Pericardiectomy: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Early Histiocytic Pleuritis Revealing Tuberculosis on Repeat Thoracoscopy: A Case Report.Cureus · 2025Article
- Recent advances in multimodality imaging-guided therapy in pericarditis.European journal of clinical investigation · 2025Review
- Pericardial Conundrum: Unmasking Tuberculosis as the Culprit.JACC. Case reports · 2025Article
- Oligosaccharide Lactate Nanoparticles Enhance Tissue Targeting: A Case Study of the Controlled Delivery of Bedaquiline to Cardiac Tissue in TB Pericarditis.Molecules (Basel, Switzerland) · 2025Article
- The clinical application value and the imaging characteristic ofBMC cardiovascular disorders · 2025Article
- 'Tuberculosis pericarditis': a case report in a high-income country.European heart journal. Case reports · 2025Article
- Case Report: Extrapulmonary tuberculosis presenting as multiple caseous pericardial masses.Frontiers in cardiovascular medicine · 2025Article
- The value of LAM and LprG in extracellular vesicles in the diagnostic and therapeutic field of renal tuberculosis.Frontiers in tuberculosis · 2025Review
- CASE REPORT:African journal of thoracic and critical care medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review provides an update on the immunopathogenesis of tuberculous pericarditis (TBP), investigations to confirm tuberculous etiology, the limitations of anti-tuberculous therapy (ATT), and recent efficacy trials. RECENT
findingsA profibrotic immune response characterizes TBP, with low levels of AcSDKP, high levels of γ-interferon and IL-10 in the pericardium, and high levels of TGF-β and IL-10 in the blood. These findings may have implications for future therapeutic targets. Despite advances in nucleic acid amplification approaches, these tests remain disappointing for TBP. Trials of corticosteroids and colchicine have had mixed results, with no impact on mortality, evidence of a reduction in rates of constrictive pericarditis and potential harm in those with advanced HIV. Small studies suggest that ATT penetrates the pericardium poorly. Given that there is a close association between high bacillary burden and mortality, a rethink about the optimal drug doses and duration may be required. The high mortality and morbidity from TBP despite use of anti-tuberculous drugs call for researches targeting host-directed immunological determinants of treatment outcome. There is also a need for the identification of steps in clinical management where interventions are needed to improve outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.