ArticleClinical oral investigations2020
Inhibition of bacterial growth on zirconia abutment with a helium cold atmospheric plasma jet treatment.
Article in Clinical oral investigations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07548931 (The Effect of Different Cold Plasma Systems on Early Microbial Colonization of Implant Healing Abutments), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Different Cold Plasma Systems on Early Microbial Colonization of Implant Healing Abutments
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- The Effectiveness of Cold Atmospheric Plasma (CAP) on Bacterial Reduction in Dental Implants: A Systematic Review.Biomolecules · 2023Pooled it
- Cold atmospheric plasma for implant surface decontamination and osseointegration: a scoping review with implications for peri-implantitis management.BMC oral health · 2026Article
- Voltage-tunable plasma-activated water: a strategy for combating peri-implantitis via dual-path biofilm disruption and vascular regeneration.Clinical oral investigations · 2026Article
- [Effects of cold atmosphere plasma treatment on the biological behavior of human gingival fibroblasts].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026Article
- Role of cold atmospheric plasma alone or combined with conventional surface treatments on shear bond strength of 3Y-TZP and 5YSZ ceramics bonded with composite resin.Biomaterial investigations in dentistry · 2026Article
- Effect of cold atmospheric plasma on common oral pathogenic microorganisms: a narrative review.Annals of medicine · 2025Review
- Unveiling the characteristics and surface modification of titanium, zirconia, and polyetheretherketone dental implants.Journal of dental sciences · 2025Review
- Helium cold atmospheric pressure plasma reduces erastin induced inflammation and ferroptosis in human gingival fibroblasts.Scientific reports · 2025Article
- Enhancement of Biocompatibility of High-Transparency Zirconia Abutments with Human Gingival Fibroblasts via Cold Atmospheric Plasma Treatment: An In Vitro Study.Journal of functional biomaterials · 2024Article
- Nonthermal Atmospheric Pressure Plasma Treatment of Endosteal Implants for Osseointegration and Antimicrobial Efficacy: A Comprehensive Review.Bioengineering (Basel, Switzerland) · 2024Review
- The integration of peri-implant soft tissues around zirconia abutments: Challenges and strategies.Bioactive materials · 2023Review
- Evaluation of Selected Properties of Dielectric Barrier Discharge Plasma Jet.Materials (Basel, Switzerland) · 2023Article
- Enhanced Antibacterial Effect on Zirconia Implant Abutment by Silver Linear-Beam Ion Implantation.Journal of functional biomaterials · 2023Article
- Effect of the Plasma Gas Type on the Surface Characteristics of 3Y-TZP Ceramic.International journal of molecular sciences · 2022Article
- In vitro and in vivo research of atmosphere pressure nonequilibrium plasmas on root canal disinfection: implication for alternative strategy for irrigation.Clinical oral investigations · 2021Article
- Surface barrier discharges for Escherichia coli biofilm inactivation: Modes of action and the importance of UV radiation.PloS one · 2021Article
- The Emerging Role of Cold Atmospheric Plasma in Implantology: A Review of the Literature.Nanomaterials (Basel, Switzerland) · 2020Review
- Cold Atmospheric Plasma: A Powerful Tool for Modern Medicine.International journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesThis study presents a surface modification method to treat the zirconia implant abutment materials using a helium cold atmospheric plasma (CAP) jet in order to evaluate its efficacy on oral bacteria adhesion and growth. MATERIALS AND
methodsYttrium-Stabilized Zirconia disks were subjected to helium CAP treatment; after the treatment, zirconia surface was evaluated using scanning electron microscopy, a contact angle measuring device, X-ray photoelectron spectroscopy for surface characteristics. The response of Streptococcus mutans and Porphyromonas gingivalis on treated surface was evaluated by a scanning electron microscopy, MTT assay, and LIVE/DEAD staining. The biofilm formation was analyzed using a crystal violet assay.
resultsAfter the helium CAP jet treatment, the zirconia surface chemistry has been changed while the surface topography remains unchanged, the bacterial growth was inhibited, and the biofilm forming decreased. As the treatment time increases, the zirconia abutment showed a better bacterial inhibition efficacy.
conclusionsThe helium CAP jet surface modification approach can eliminate bacterial growth on zirconia surface with surface chemistry change, while surface topography remained. CLINICAL RELEVANCE: Soft tissue seal around dental implant abutment plays a crucial role in maintaining long-term success. However, it is weaker than periodontal barriers and vulnerable to bacterial invasion. CAP has a potential prospect for improving soft tissue seal around the zirconia abutment, therefore providing better esthetics and most of all, prevent peri-implant lesions from happening.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.