Evidence map›Paper›PMID 31939615›Full record

ReviewInternational journal of oncology2020

PET/CT and PET/MRI in ophthalmic oncology (Review).

Maria S Kalemaki, Apostolos H Karantanas, Dimitris Exarchos, Efstathios T Detorakis, Odysseas Zoras, Kostas Marias, Corina Millo, Ulas Bagci, Ioannis Pallikaris, Andreas Stratis and 7 more

Open access · hybridAbstract readReview
In one paragraph

Review in International journal of oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Advances in Positron Emission Tomography/Computed Tomography for Diagnosing and Managing Primary Posterior Uveal Melanoma.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Review
  9. Article
  10. Robust vs. Non-robust radiomic features: the quest for optimal machine learning models using phantom and clinical studies.Cancer imaging : the official publication of the International Cancer Imaging Society · 2025
    Article
  11. Progressive Unilateral Proptosis and [World journal of nuclear medicine · 2025
    Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. PET/MRI in Pediatric Neuroimaging: Primer for Clinical Practice.AJNR. American journal of neuroradiology · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 2 countries.

Maria S KalemakiDepartment of Ophthalmology, Venizeleio General Hospital of Heraklion, 71409 Heraklion, Greece.
Apostolos H KarantanasDepartment of Radiology, Medical School, University of Crete, 71003 Heraklion, Greece.
Dimitris ExarchosDepartment of CT‑MRI and PET/CT, Evangelismos Hospital, 10676 Athens, Greece.
Efstathios T DetorakisDepartment of Ophthalmology, Medical School, University of Crete, 71003 Heraklion, Greece.
Odysseas ZorasDepartment of Surgical Oncology, Medical School, University of Crete, 71003 Heraklion, Greece.
Kostas MariasFoundation for Research and Technology Hellas (FORTH), Computational Biomedicine Laboratory (CBML), 70013 Heraklion, Greece.
Corina MilloPositron Emission Tomography Department, Clinical Center (CC), National Institutes of Health (NIH), Bethesda, MD 20814, USA.
Ulas BagciCenter for Research in Computer Vision (CRCV), University of Central Florida (UCF), Orlando, FL 32816, USA.
Ioannis PallikarisDepartment of Ophthalmology, Medical School, University of Crete, 71003 Heraklion, Greece.
Andreas StratisFoundation for Research and Technology Hellas (FORTH), Computational Biomedicine Laboratory (CBML), 70013 Heraklion, Greece.
Ioannis KaratzanisFoundation for Research and Technology Hellas (FORTH), Computational Biomedicine Laboratory (CBML), 70013 Heraklion, Greece.
Kostas PerisinakisDepartment of Medical Physics, Medical School, University of Crete, 71003 Heraklion, Greece.
Pavlos KoutentakisDepartment of Ophthalmology, Venizeleio General Hospital of Heraklion, 71409 Heraklion, Greece.
Georgios A KontadakisDepartment of Ophthalmology, Medical School, University of Crete, 71003 Heraklion, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece.
Aristidis TsatsakisLaboratory of Forensic Sciences and Toxicology, Medical School, University of Crete, 71003 Heraklion, Greece.
Georgios Z PapadakisDepartment of Radiology, Medical School, University of Crete, 71003 Heraklion, Greece.
University of Crete · GRFoundation for Research and Technology Hellas · GRThe General Hospital of Heraklion "Venizeleio-Pananio" · GREvangelismos Hospital · GRNational Institutes of Health · USUniversity of Central Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Orbital and ocular anatomy is quite complex, consisting of several tissues, which can give rise to both benign and malignant tumors, while several primary neoplasms can metastasize to the orbital and ocular space. Early detection, accurate staging and re‑staging, efficient monitoring of treatment response, non‑invasive differentiation between benign and malignant lesions, and accurate planning of external radiation treatment, are of utmost importance for the optimal and individualized management of ophthalmic oncology patients. Addressing these challenges requires the employment of several diagnostic imaging techniques, such as high‑definition digital fundus photography, ultrasound imaging, optical coherence tomography, optical coherence tomography (OCT)‑angiography, computed tomography (CT) and magnetic resonance imaging (MRI). In recent years, technological advances have enabled the development of hybrid positron emission tomography (PET)/CT and PET/MRI systems, setting new standards in cancer diagnosis and treatment. The capability of simultaneously targeting several cancer‑related biochemical procedures using positron emitting‑radiopharmaceuticals, while morphologically characterizing lesions by CT or MRI, together with the intrinsic quantitative capabilities of PET‑imaging, provide incremental diagnostic information, enabling accurate, highly efficient and personalized treatment strategies. Aim of the current review is to discuss the current applications of hybrid PET/CT and PET/MRI imaging in the management of patients presenting with the most commonly encountered orbital and ocular tumors.

Indexed as

Multimodal ImagingEye NeoplasmsHumansMagnetic Resonance ImagingOrbital NeoplasmsPositron-Emission TomographyRadiopharmaceuticalsTomography, X-Ray ComputedRadiopharmaceuticals

Identifiers

PMID31939615
PMCPMC6959466
OpenAlexW2998267860

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.