Evidence map›Paper›PMID 31939475›Full record

ArticleChemical Society reviews2020

Catechol-functionalized hydrogels: biomimetic design, adhesion mechanism, and biomedical applications.

Wei Zhang, Ruixing Wang, ZhengMing Sun, Xiangwei Zhu, Qiang Zhao, Tengfei Zhang, Aleksander Cholewinski, Fut Kuo Yang, Boxin Zhao, Rattapol Pinnaratip and 2 more

Abstract read
In one paragraph

Article in Chemical Society reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 211 papers.

0numbers the graph read from it
0cells of the map it votes in
211citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

211 citing papers in PubMed.

  1. Review
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  5. Enhancing dentin bonding with catechol-based monomers by tailoring photoinitiator systems to overcome radical inhibition.Dental materials : official publication of the Academy of Dental Materials · 2026
    Article
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  7. Review
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151 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Wei ZhangJiangsu Key Laboratory of Advanced Metallic Materials, School of Materials Science and Engineering, Southeast University, Nanjing, 211189, China. w69zhang@seu.edu.cn zmsun@seu.edu.cn.ORCID http://orcid.org/0000-0002-4700-2658
Ruixing WangJiangsu Key Laboratory of Advanced Metallic Materials, School of Materials Science and Engineering, Southeast University, Nanjing, 211189, China. w69zhang@seu.edu.cn zmsun@seu.edu.cn.
ZhengMing SunJiangsu Key Laboratory of Advanced Metallic Materials, School of Materials Science and Engineering, Southeast University, Nanjing, 211189, China. w69zhang@seu.edu.cn zmsun@seu.edu.cn.ORCID http://orcid.org/0000-0001-9798-9385
Xiangwei ZhuKey Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China. zhaoq@hust.edu.cn.
Qiang ZhaoKey Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430074, China. zhaoq@hust.edu.cn.ORCID http://orcid.org/0000-0002-0643-5916
Tengfei ZhangJiangsu Key Laboratory of Electrochemical Energy-Storage Technologies, College of Materials Science and Technology, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China.
Aleksander CholewinskiDepartment of Chemical Engineering, Waterloo Institute for Nanotechnology, Centre for Bioengineering and Biotechnology, University of Waterloo, Ontario N2L 3G1, Canada. zhaob@uwaterloo.ca.ORCID http://orcid.org/0000-0002-8158-7776
Fut Kuo YangDepartment of Chemical Engineering, Waterloo Institute for Nanotechnology, Centre for Bioengineering and Biotechnology, University of Waterloo, Ontario N2L 3G1, Canada. zhaob@uwaterloo.ca.ORCID http://orcid.org/0000-0002-6010-726X
Boxin ZhaoDepartment of Chemical Engineering, Waterloo Institute for Nanotechnology, Centre for Bioengineering and Biotechnology, University of Waterloo, Ontario N2L 3G1, Canada. zhaob@uwaterloo.ca.ORCID http://orcid.org/0000-0003-4739-1339
Rattapol PinnaratipDepartment of Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931, USA. bplee@mtu.edu.
Pegah Kord ForooshaniDepartment of Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931, USA. bplee@mtu.edu.
Bruce P LeeDepartment of Biomedical Engineering, Michigan Technological University, Houghton, Michigan 49931, USA. bplee@mtu.edu.ORCID http://orcid.org/0000-0002-6529-0032

Funding

Biomimetic Tissue Adhesive with Mechanically Tough Hydrogel SupportR15GM104846 · NIGMS · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI LEE, BRUCE P · 2013 to 2016
$757k
NIGMS NIH HHS R15 GM104846
6 · The paper itself

Abstract

Hydrogels are a unique class of polymeric materials that possess an interconnected porous network across various length scales from nano- to macroscopic dimensions and exhibit remarkable structure-derived properties, including high surface area, an accommodating matrix, inherent flexibility, controllable mechanical strength, and excellent biocompatibility. Strong and robust adhesion between hydrogels and substrates is highly desirable for their integration into and subsequent performance in biomedical devices and systems. However, the adhesive behavior of hydrogels is severely weakened by the large amount of water that interacts with the adhesive groups reducing the interfacial interactions. The challenges of developing tough hydrogel-solid interfaces and robust bonding in wet conditions are analogous to the adhesion problems solved by marine organisms. Inspired by mussel adhesion, a variety of catechol-functionalized adhesive hydrogels have been developed, opening a door for the design of multi-functional platforms. This review is structured to give a comprehensive overview of adhesive hydrogels starting with the fundamental challenges of underwater adhesion, followed by synthetic approaches and fabrication techniques, as well as characterization methods, and finally their practical applications in tissue repair and regeneration, antifouling and antimicrobial applications, drug delivery, and cell encapsulation and delivery. Insights on these topics will provide rational guidelines for using nature's blueprints to develop hydrogel materials with advanced functionalities and uncompromised adhesive properties.

Indexed as

BiomimeticsAdhesivesCatecholsHydrogelsSurface PropertiesAdhesivesCatecholsHydrogels

Identifiers

PMID31939475
PMCPMC7208057

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.