Evidence map›Paper›PMID 31939316›Full record

Trial reportClimacteric : the journal of the International Menopause Society2020

Association of oral estradiol dose/levels with coagulation measures in early/late postmenopausal women.

I Sriprasert, H N Hodis, B Bernick, S Mirkin, W J Mack

Abstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Climacteric : the journal of the International Menopause Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Chapter 3. Impact of estrogens on hemostasis.Frontiers in endocrinology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

I SriprasertDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.ORCID 0000-0001-5367-762X
H N HodisDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
B BernickTherapeuticsMD, Boca Raton, FL, USA.
S MirkinTherapeuticsMD, Boca Raton, FL, USA.
W J MackDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

Funding

Biologic Response of Menopausal Women to 17B-EstradiolR01AG024154 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HODIS, HOWARD NEIL · 2004 to 2012
$13.8M
MECHANISMS UNDERLYING THE AGE-RELATED ATHEROPROTECTIVE EFFECTS OF HORMONE THERAPYR01AG059690 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HODIS, HOWARD NEIL · 2018 to 2022
$3.6M
NIA NIH HHS R01 AG024154NIA NIH HHS R01 AG059690
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

PostmenopauseAdministration, OralAdultAgedBlood Coagulation FactorsDouble-Blind MethodEstradiolEstrogen Replacement TherapyFemaleHumansMiddle AgedProthrombin TimeUnited StatesBlood Coagulation FactorsEstradiolEstradiolhormonesmenopausethrombosiswomen

Identifiers

PMID31939316
PMCPMC7853766

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.