Evidence map›Paper›PMID 31939019›Full record

ArticleEnvironmental science and pollution research international2021

Exploring the powerful phytoarsenal of white grape marc against bacteria and parasites causing significant diseases.

José-Luis Rodríguez Rama, Natalia Mallo, Marco Biddau, Francisco Fernandes, Trinidad de Miguel, Lilach Sheiner, Altino Choupina, Marta Lores

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The Search for Drugs Derived from Natural Products forCurrent topics in medicinal chemistry · 2024
    Pooled it
  2. Review
  3. Article
  4. Grape Marc as a Functional Feed Ingredient for Farmed SnailsAnimals : an open access journal from MDPI · 2025
    Article
  5. Article
  6. Evaluation of Antimicrobial Activity ofPlants (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
  12. Multicomponent Polyphenolic Extracts fromPlants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

José-Luis Rodríguez Rama *Department of Microbiology and Parasitology, University of Santiago de Compostela, Santiago de Compostela, E-15782, A Coruña, Spain.
Natalia Mallo *Wellcome Centre for Integrative Parasitology. Department of Infection, Immunity and Inflamation., University of Glasgow, 120 University Place, Glasgow, UK.
Marco BiddauWellcome Centre for Integrative Parasitology. Department of Infection, Immunity and Inflamation., University of Glasgow, 120 University Place, Glasgow, UK.
Francisco FernandesDepartment of Socioeconomical systems, I. Politécnico Bragança, 5300-253, Terras Trás-os-Montes, Portugal.
Trinidad de MiguelDepartment of Microbiology and Parasitology, University of Santiago de Compostela, Santiago de Compostela, E-15782, A Coruña, Spain. trinidad.demiguel@usc.es.ORCID http://orcid.org/0000-0002-0389-6610
Lilach SheinerWellcome Centre for Integrative Parasitology. Department of Infection, Immunity and Inflamation., University of Glasgow, 120 University Place, Glasgow, UK.
Altino ChoupinaDepartment of Socioeconomical systems, I. Politécnico Bragança, 5300-253, Terras Trás-os-Montes, Portugal.
Marta LoresDepartment of Analytical Chemistry, Nutrition and Food Science, Laboratory of Research and Development of Analytical Solutions (LIDSA), University of Santiago de Compostela, Santiago de Compostela, E-15782, A Coruña, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural extracts containing high polyphenolic concentration possess antibacterial, anti-parasitic and fungicidal activities. The present research characterises two extracts based on white grape marc, a winemaking by-product, describing their physicochemical features and antimicrobial capacities. The main components of these extracts are phenolic acids, flavan-3-ols and their gallates and flavonols and their glycosides. As a result of this complex composition, the extracts showed pronounced bioactivities with potential uses in agricultural, pharmaceutical and cosmetic industries. Polyphenol compounds were extracted by using hydro-organic solvent mixtures from the by-product of Albariño white wines (Galicia, NW Spain) production. The in vitro antimicrobial activity of these extracts was evaluated on Gram-positive and Gram-negative bacteria and Apicomplexan and Oomycota parasites. Microbial species investigated are causing agents of several human and animal diseases, such as foodborne illnesses (Bacillus cereus, Escherichia coli, Salmonella enterica, and Toxoplasma gondii), skin infections and/or mastitis (Staphylococcus aureus and Streptococcus uberis), malaria (Plasmodium falciparum) and plant infections as "chestnut ink" or "root rot" (Phytophthora cinnamomi). Both extracts showed activity against all the tested species, being nontoxic for the host. So, they could be used for the development of biocides to control a wide range of pathogenic agents and contribute to the enhancement of winemaking industry by-products.

Indexed as

ParasitesVitisAnimalsAnti-Bacterial AgentsBacteriaGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsPlant ExtractsSpainStreptococcusAnti-Bacterial AgentsPlant ExtractsAntibacterialAnti-parasiticEnhancement of winemaking by-productsGrape marcNatural extractPolyphenols

Identifiers

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.