Evidence map›Paper›PMID 31938967›Full record

SynthesisNeurosurgical review2021

Advances in surgical hemostasis: a comprehensive review and meta-analysis on topical tranexamic acid in spinal deformity surgery.

Nida Fatima, Megan E Barra, Russel Joseph Roberts, Elie Massaad, Muhamed Hadzipasic, Ganesh M Shankar, John H Shin

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nida FatimaDepartment of Neurosurgery, Massachusetts General Hospital, Boston, USA. NFATIMA@mgh.harvard.edu.ORCID http://orcid.org/0000-0002-0951-0758
Megan E BarraDepartment of Clinical Pharmacist, Massachusetts General Hospital, Boston, USA.
Russel Joseph RobertsDepartment of Clinical Pharmacist, Massachusetts General Hospital, Boston, USA.
Elie MassaadDepartment of Neurosurgery, Massachusetts General Hospital, Boston, USA.
Muhamed HadzipasicDepartment of Neurosurgery, Massachusetts General Hospital, Boston, USA.
Ganesh M ShankarDepartment of Neurosurgery, Massachusetts General Hospital, Boston, USA.
John H ShinDepartment of Neurosurgery, Massachusetts General Hospital, Boston, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tranexamic acid (TXA) is an effective and commonly used hemostatic agent for perioperative blood loss in various surgical specialties. It is being increasingly used in spinal deformity surgery. We aimed to evaluate the safety and efficacy of topical TXA (tTXA) compared to both placebo and/or intravenous (IV) TXA in patients undergoing spinal deformity surgery. We conducted a systematic review of the electronic databases using different MeSH terms from January 1970 to August 2019. Pooled and subgroup analysis was performed using fixed and random-effect model based upon the heterogeneity (I

Indexed as

Administration, TopicalAntifibrinolytic AgentsBlood Loss, SurgicalHemostatic TechniquesHumansNeurosurgical ProceduresScoliosisSpineTranexamic AcidAntifibrinolytic AgentsTranexamic AcidBlood lossEfficacySafetyScoliosisSpinal deformitySpine fusionTranexamic acid

Identifiers

PMID31938967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.