Evidence map›Paper›PMID 31938963›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Mental and physical health status among chronic hepatitis B patients.

Yihe G Daida, Joseph A Boscarino, Anne C Moorman, Mei Lu, Loralee B Rupp, Stuart C Gordon, Eyasu H Teshale, Mark A Schmidt, Philip R Spradling, Chronic Hepatitis Cohort Study Investigators

Abstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The social determinants of health-related quality of life among people with chronic disease: a systematic literature review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  2. Article
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  8. Stressful life events in electronic health records: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2024
    Article
  9. Article
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  12. Screening and Testing for Hepatitis B Virus Infection: CDC Recommendations - United States, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yihe G DaidaCenter for Integrated Health Care Research, Kaiser Permanente Hawaii, 501 Alakawa St, Suite 201, Honolulu, HI, 96817, USA. Yihe.G.Daida@kp.org.ORCID http://orcid.org/0000-0003-1628-0476
Joseph A BoscarinoDepartment of Epidemiology & Health Services Research, Geisinger Clinic, 100 N. Academy Avenue, Danville, PA, 17822, USA.
Anne C MoormanDivision of Viral Hepatitis; National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS G-37, Atlanta, GA, 30333, USA.
Mei LuHenry Ford Health System, Center for Health Policy & Health Services Research, One Ford Place, Detroit, MI, 48202, USA.
Loralee B RuppHenry Ford Health System, Center for Health Policy & Health Services Research, One Ford Place, Detroit, MI, 48202, USA.
Stuart C GordonHenry Ford Health System, Center for Health Policy & Health Services Research, One Ford Place, Detroit, MI, 48202, USA.
Eyasu H TeshaleLead, Epidemiology Research Team; Epidemiology and Surveillance Branch; Division of Viral Hepatitis; National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS G-37, Atlanta, GA, 30333, USA.
Mark A SchmidtKaiser Permanente Northwest, Center for Health Research, 3800 N. Interstate Ave, Portland, OR, 97227, USA.
Philip R SpradlingDivision of Viral Hepatitis; National Center for HIV, Viral Hepatitis, STD, and TB Prevention, Centers for Disease Control and Prevention, 1600 Clifton Rd, NE, MS G-37, Atlanta, GA, 30333, USA.
Chronic Hepatitis Cohort Study Investigators

Funding

CDC HHS 1U18PS005154Gilead Sciences IN-US-337-3957Intramural CDC HHS CC999999
6 · The paper itself

Abstract

purposeLittle is known about health-related quality of life (HRQoL) in patients with chronic hepatitis B virus (CHB) infection in the United States. Our goal is to understand factors associated with HRQoL in this population.

methodsWe conducted a survey to assess HRQoL and behavioral risks among patients with CHB infection from four large U.S. health care systems. Primary outcomes were generated from the SF-8 scale to assess HRQoL, as measured by the mental component scores (MCS) and physical component scores (PCS). The survey also measured socio-demographic information, hepatitis-related behavioral risk factors, treatment exposure/history, stress, and social support. We supplemented survey data with electronic health records data on patient income, insurance, disease severity, and comorbidities. Multivariate analysis was used to estimate and compare adjusted least square means of MCS and PCS, and examine which risk factors were associated with lower MCS and PCS.

resultsNine hundred sixty-nine patients (44.6%) responded to the survey. Current life stressors and unemployment were associated with both lower MCS and PCS results in multivariate analyses. Lower MCS was also associated with White race and low social support, while lower PCS was also associated with Medicaid insurance.

conclusionsStressful life events and unemployment were related to mental and physical health status of CHB patients. Those who have social support have better mental health; White and Medicaid patients are more likely to have poorer mental and physical health, respectively. Management of CHB patients should include stress management, social support, and financial or employment assistance.

Indexed as

Health StatusAdultAgedComorbidityFemaleHepatitis B, ChronicHumansMaleMental HealthMiddle AgedMultivariate AnalysisQuality of LifeRisk FactorsSocial SupportStress, PsychologicalSurveys and QuestionnairesCHBChronicHepatitisHRQoLSF-8

Identifiers

PMID31938963
PMCPMC8281322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.