Evidence map›Paper›PMID 31938835›Full record

ArticlePediatric surgery international2020

Intracranial pressure monitoring associated with increased mortality in pediatric brain injuries.

Patrick T Delaplain, Areg Grigorian, Michael Lekawa, Michael Mallicote, Victor Joe, Sebastian D Schubl, Catherine M Kuza, Matthew Dolich, Jeffry Nahmias

Open access · bronzeAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric surgery international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Utility of intracranial pressure monitoring in patients with traumatic brain injuries: a propensity score matching analysis of TQIP data.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  6. Article
  7. Review
  8. Predicting inpatient mortality in pediatric traumatic brain injury: insights from a national database.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  9. Management Strategies Based on Multi-Modality Neuromonitoring in Severe Traumatic Brain Injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023
    Review
  10. Optic nerve sheath diameter and pulsatility index for the diagnosis and follow-up in pediatric traumatic brain injury: a prospective observational cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Patrick T DelaplainDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA. pdelapla@uci.edu.ORCID http://orcid.org/0000-0003-1799-6943
Areg GrigorianDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA.
Michael LekawaDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA.
Michael MallicoteDepartment of Pediatric Surgery, Children's Hospital Los Angeles, 4650 Sunset Blvd., Mailstop #100, Los Angeles, CA, 90027, USA.
Victor JoeDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA.
Sebastian D SchublDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA.
Catherine M KuzaDepartment of Anesthesiology, University of Southern California, 1450 San Pablo Street Suite 360, Los Angeles, CA, 90033, USA.
Matthew DolichDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA.
Jeffry NahmiasDepartment of Surgery, University of California, Irvine Medical Center, 333 City Blvd West, Suite 1600, Orange, CA, 92868, USA.
University of California, Irvine Medical Center · USChildren's Hospital of Los Angeles · USUniversity of Southern California · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUtilization of ICP monitors for pediatric patients is low and varies between centers. We hypothesized that in more severely injured patients (GCS 3-4), there would be a decreased mortality associated with invasive monitoring devices.

methodsThe pediatric Trauma Quality Improvement Program (TQIP) was queried for patients aged ≤ 16 years meeting criteria for invasive monitors. Our primary outcome was mortality. Patients with ICP monitoring were compared to those without. A logistic regression was used to examine the risk of mortality.

resultsOf 3,808 patients, 685 (18.0%) underwent ICP monitoring. ICP monitors were associated with increased risk of mortality (OR 1.82, CI 1.36-2.44, p < 0.001). A secondary analysis including type of invasive ICP monitor and dividing GCS into 3 categories revealed both intraventricular drain (OR 1.89, CI 1.3-2.7, p = 0.001) and intraparenchymal pressure monitor (OR 1.86, CI 1.32-2.6, p < 0.001) to be independently associated with an increased likelihood of mortality regardless of GCS, while intraparenchymal oxygen monitoring was not (OR 0.47, CI 0.11-2.05, p = 0.316). The strongest effect was seen in those patients with a GCS of 5-6.

conclusionICP monitors are an independent risk factor for mortality, particularly with intraventricular drains and intraparenchymal monitors in patients with a GCS 5-6.

Indexed as

Brain InjuriesChildChild, PreschoolFemaleHumansIntracranial PressureMaleMonitoring, PhysiologicPrognosisRisk FactorsSurvival RateUnited StatesIntracranial hypertensionIntracranial pressure (ICP) monitorPediatric traumaTraumatic brain injury (TBI)

Identifiers

PMID31938835
PMCPMC7223517
OpenAlexW2998974967

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.