Evidence map›Paper›PMID 31938756›Full record

ArticleBioactive materials2020

Investigation of Mg-Zn-Y-Nd alloy for potential application of biodegradable esophageal stent material.

Shuo Wang, Xueqi Zhang, Jingan Li, Changsheng Liu, Shaokang Guan

Abstract read
In one paragraph

Article in Bioactive materials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  5. Polymer composite microspheres loadingBiomaterials research · 2023
    Article
  6. Review
  7. Article
  8. Article
  9. Article
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  11. Bioactive materials · 2022
    Article
  12. Article
  13. Article
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  19. Bioactive materials · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shuo WangSchool of Materials Science and Engineering, Henan Key Laboratory of Advanced Magnesium Alloy, Key Laboratory of Materials Processing and Mold Technology, Ministry of Education, Zhengzhou University, 100 Science Road, Zhengzhou, 450001, PR China.
Xueqi ZhangSchool of Materials Science and Engineering, Henan Key Laboratory of Advanced Magnesium Alloy, Key Laboratory of Materials Processing and Mold Technology, Ministry of Education, Zhengzhou University, 100 Science Road, Zhengzhou, 450001, PR China.
Jingan LiSchool of Materials Science and Engineering, Henan Key Laboratory of Advanced Magnesium Alloy, Key Laboratory of Materials Processing and Mold Technology, Ministry of Education, Zhengzhou University, 100 Science Road, Zhengzhou, 450001, PR China.
Changsheng LiuSchool of Materials Science and Engineering, Henan Key Laboratory of Advanced Magnesium Alloy, Key Laboratory of Materials Processing and Mold Technology, Ministry of Education, Zhengzhou University, 100 Science Road, Zhengzhou, 450001, PR China.
Shaokang GuanSchool of Materials Science and Engineering, Henan Key Laboratory of Advanced Magnesium Alloy, Key Laboratory of Materials Processing and Mold Technology, Ministry of Education, Zhengzhou University, 100 Science Road, Zhengzhou, 450001, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, due to unhealthy dietary habits and other reasons, advanced esophageal cancer patients are on the rise, threatening human health and life safety at all times. Stents implantation as an important complementary or alternative method for chemotherapy has been widely applied in clinics. However, the adhesion and proliferation of pathological cells, such as tumor cells, fibroblasts and epithelial cells, may interfere the efficacy of stents. Further multiple implantation due to restenosis may also bring pain to patients. In this contribution, we preferred a biodegradable material Mg-Zn-Y-Nd alloy for potential application of esophageal stent. The hardness testing showed that Mg-Zn-Y-Nd alloy owned less mechanical properties compared with the commercial esophageal stents material, 317L stainless steel (317L SS), while Mg-Zn-Y-Nd displayed significantly better biodegradation than 317L SS. Cell apoptosis assay indicated Mg-Zn-Y-Nd inhibited adhesion and proliferation of tumor cells, fibroblasts and epithelial cells. Our research suggested potential application of Mg-Zn-Y-Nd alloy as a novel material for biodegradable esophageal stent.

Indexed as

BiocompatibilityBiodegradable metal materialEsophageal stentHardnessMg–Zn–Y–Nd alloy

Identifiers

PMID31938756
PMCPMC6953596

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.