Evidence map›Paper›PMID 31938730›Full record

ArticleOsteoporosis and sarcopenia2019

Serum 25-hydroxyvitamin D concentrations in Japanese postmenopausal women with osteoporotic fractures.

Yoshiaki Yamanaka, Kunitaka Menuki, Yukichi Zenke, Satoshi Ikeda, Eiji Hatakeyama, Kimiaki Kawano, Satoshi Nishida, Hiroaki Tanaka, Keiichi Yumisashi, Akinori Sakai

Open access · diamondAbstract read
In one paragraph

Article in Osteoporosis and sarcopenia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Review
  6. High-Intensity Physical Activity with High Serum Vitamin D Levels is Associated with a Low Prevalence of Osteopenia and Osteoporosis: A Population-Based Study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Yoshiaki YamanakaDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Kunitaka MenukiDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Yukichi ZenkeDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Satoshi IkedaDepartment of Orthopaedic Surgery, Ken-Ai Memorial Hospital, Fukuoka, Japan.
Eiji HatakeyamaDepartment of Orthopaedic Surgery, Fukuoka Shin Mizumaki Hospital, Fukuoka, Japan.
Kimiaki KawanoDepartment of Orthopaedic Surgery, Ashiya Central Hospital, Fukuoka, Japan.
Satoshi NishidaDepartment of Orthopaedic Surgery, Social Insurance Nogata Hospital, Nogata, Japan.
Hiroaki TanakaDepartment of Orthopaedic Surgery, Kurate Hospital, Kurate, Japan.
Keiichi YumisashiDepartment of Emergency Medicine, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Akinori SakaiDepartment of Orthopaedic Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
University of Occupational and Environmental Health Japan · JPAshiya University · JPFukuoka Hospital · JPFukuoka Kinen Hospital · JPSaigata National Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the vitamin D status in postmenopausal women with osteoporotic fractures, determine its concentration by fracture site at the clinical setting, and compare the proportion of vitamin D deficiency with that reported in literature.

methodsThe prospective study included 317 postmenopausal women with osteoporotic fractures who were treated consecutively from 2016 to 2018. After obtaining informed consent for participation in the seamless treatment of osteoporosis against fractures study, which is our initiative to prevent secondary osteoporotic fractures, we registered the patients, examined bone mineral density (BMD) at the unfractured femoral neck and lumbar spine, serum 25-hydroxyvitamin D (25(OH)D) concentration, blood chemistry, and bone turnover markers.

resultsThe mean age of the patients was 80.7 years. Moreover, 78% of patients of all fractures had 25(OH)D concentration < 20 ng/mL, whereas 12% of patients had 25(OH)D concentration ≥ 30 ng/mL 25(OH)D concentration in hip fractures was significantly lower than that in vertebral or distal radius fractures (P < 0.05). Multiple regression analysis revealed that 25(OH)D concentration is significantly associated with femoral neck BMD (β = 0.16; 95% confidence interval [CI], 0.78-12.17, P = 0.03) and serum albumin concentration (β = 0.21; 95% CI, 0.62-2.96, P < 0.001) in patients with 25(OH)D concentration < 30 ng/mL.

conclusionsThe results of this study show that the proportion of postmenopausal women with osteoporotic fractures who had vitamin D deficiency was higher than the proportion in previous reports that examined general postmenopausal women (35.2%-52.0%).

Indexed as

25-hydroxyvitamin DBone mineral densityFractureOsteoporosisPostmenopausal women

Identifiers

PMID31938730
PMCPMC6953523
OpenAlexW2992811231

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.