Evidence map›Paper›PMID 31938541›Full record

SynthesisAntimicrobial resistance and infection control2020

Risk factors for quinolone-resistant

Dong-Mei Zhu, Qiu-Hong Li, Yan Shen, Qin Zhang

Registry-linked trialOpen access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Antimicrobial resistance and infection control, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06305455 (Change in the Resistance Profile of Escherichia Coli in Infections of Community Origin), which is not on this map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06305455 unknown statusnot on this mapstarted 2024, after this paper: background citation

Change in the Resistance Profile of Escherichia Coli in Infections of Community Origin: The Importance of Antimicrobial Stewardship

TypeobservationalSponsorJosé Raimundo Araujo de AzevedoRan2024 to 2024Enrolled200ConditionsAntimicrobial ResistanceArmsEscherichia coli ESBL
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. [Antimicrobial resistance characteristics ofZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2026
    Article
  2. Trends in UropathogenicOpen forum infectious diseases · 2025
    Article
  3. Antimicrobial susceptibility and genetic profiles of Escherichia coli isolated from poultry hatcheries in the state of Rio Grande do Sul, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Article
  5. Review
  6. Impact of diabetic ketoacidosis on outcomes in hospitalized diabetic patients withProceedings (Baylor University. Medical Center) · 2024
    Article
  7. Article
  8. Description of Antimicrobial-ResistantVeterinary sciences · 2023
    Article
  9. Article
  10. Polyhexamethylene biguanide promotes adaptive cross-resistance to gentamicin inFrontiers in cellular and infection microbiology · 2023
    Article
  11. Article
  12. Multidrug-ResistantThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  13. Infections in Hospitalized Cancer Patients.World journal of oncology · 2021
    Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dong-Mei ZhuDepartment of Hospital Infection Control, Chongqing Health Center for Women and Children, 120 Longshan Road, Chongqing, Chongqing, 400013 China.
Qiu-Hong LiDepartment of Clinical Laboratory, Chongqing Health Center for Women and Children, Chongqing, Chongqing, 400013 China.
Yan ShenDepartment of Clinical Laboratory, Chongqing Health Center for Women and Children, Chongqing, Chongqing, 400013 China.
Qin ZhangDepartment of Hospital Infection Control, Chongqing Health Center for Women and Children, 120 Longshan Road, Chongqing, Chongqing, 400013 China.
Chongqing Maternal and Child Health Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial resistance to quinolone is rising worldwide, especially in Methods: A systematic search was performed to collect published data in the EMBASE, PubMed, and the Cochrane Library up to April 2019. Risk factors were analyzed using the pooled odds ratio (ORs) with 95% confidence interval (CIs). Results: Twenty-seven trials involving 67,019 participants were included in the present study. The following risk factors associated with QREC infection were identified: (1) male (OR = 1.41), (2) hepatic cirrhosis (OR = 2.05), (3) diabetes mellitus (OR = 1.62), (4) cardiovascular disease (OR = 1.76), (5) neurogenic bladder (OR = 8.66), (6) renal dysfunction (OR = 2.47), (7) transplantation (OR = 2.37), (8) urinary tract infection (OR = 2.79) and urinary tract abnormality (OR = 1.85), (9) dementia (OR = 5.83), (10) heart failure (OR = 5.63), (11) neurologic disease (OR = 2.80), (12) immunosuppressive drugs (OR = 2.02), (13) urinary catheter (OR = 4.39), (14) nursing home resident (OR = 4.63), (15) prior surgery (OR = 2.54), (16) quinolones (OR = 7.67), (17) other antibiotics (OR = 2.74), (18) hospitalization (OR = 2.06) and (19) nosocomial infection acquisition (OR = 2.35). Conclusions: QREC infection was associated with nineteen risk factors including prior quinolones use, hospitalization, and several comorbidities. Reducing exposure to these risk factors and modification of antibiotic use are important to prevent quinolone resistance.

Indexed as

Drug Resistance, BacterialEscherichia coliEscherichia coli InfectionsFemaleHumansMaleOdds RatioQuinolonesRisk FactorsSex CharacteristicsQuinolonesEscherichia coliInfectionMeta-analysisQuinoloneResistanceRisk factor

Identifiers

PMID31938541
PMCPMC6953284
OpenAlexW3006445257

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.