Evidence map›Paper›PMID 31938416›Full record

ArticleInternational journal of clinical and experimental pathology2018

Expression of miR-551b and its effect on apoptosis in human gastric carcinoma.

Yanan Wang, Xiangyu Fan, Fang Xu, Pei Zhang, Yaning Wei, Shujie Cheng, Po Zhao

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 79% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yanan WangDepartment of Pathology, Affiliated Hospital of Hebei University Baoding 071000, Hebei, PR China.
Xiangyu FanDepartment of Pathology, Affiliated Hospital of Hebei University Baoding 071000, Hebei, PR China.
Fang XuDepartment of Pathology, Affiliated Hospital of Hebei University Baoding 071000, Hebei, PR China.
Pei ZhangDepartment of Pathology, Affiliated Hospital of Hebei University Baoding 071000, Hebei, PR China.
Yaning WeiDepartment of Oncology, Affiliated Hospital of Hebei University Baoding 071000, Hebei, PR China.
Shujie ChengDepartment of Surgery, Affiliated Hospital of Hebei University Baoding 071000, Hebei, PR China.
Po ZhaoDepartment of Pathology, PLA General Hospital Beijing 100853, PR China.
Affiliated Hospital of Hebei University · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

miR-551b has been reported to be involved in tumorigenesis, cell invasion, and metastasis in gastric cancer but the mechanism remains unclear. In this study, in an attempt to address this question, we examined expression of miR-551b in gastric tumors and adjacent normal tissue. We transfected SGC-7901 gastric cancer cells with miRNA non-sense sequences (NC group), miR-551b mimics (miR-551b mimic group), and miR-551b inhibitors (miR-551b inhibitor group) to investigate the role of miR-551b in autophagic apoptosis. In gastric tissue, our real-time PCR results revealed that expression of miR-551b was significantly downregulated and the relative expression of miR-551b (1.75 ± 0.13) was significantly lower than in normal tissue (2.47 ± 0.38) (

Indexed as

autophagic apoptosisgastric cancermiR-551bmiRNA

Identifiers

PMID31938416
PMCPMC6958274
OpenAlexW3026210368

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.