ArticleInternational journal of clinical and experimental pathology2018
Primary epithelioid angiosarcoma of the adrenal gland: aggressive histological features and clinical behavior.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Adrenal angiosarcoma, a rare neoplasm: a case report and a literature review.Gland surgery · 2026Article
- Recurrent fever leading to the diagnosis of an angiosarcoma of the adrenal gland: a case report.Journal of medical case reports · 2024Article
- Epithelioid angiosarcoma of the adrenal gland with metastasis: a case report and literature review.Annals of medicine and surgery (2012) · 2023Article
- A Rare Case of Primary Adrenal Epithelioid Angiosarcoma.The American journal of case reports · 2023Article
- Primary thyroid angiosarcoma in a non-endemic region - a rare case.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie · 2020Article
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Authors and funding
8 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary adrenal epithelioid angiosarcoma (PAEA) is an exceedingly rare and high-grade malignant neoplasm with an epithelioid appearance morphologically. To the best of our knowledge, only 35 cases of PAEA have previously been reported in English literature. Here, we present our 7-year experience (2010-2017) with adrenal lesions at our Clinical Pathological Diagnosis Center. Of more than 1,800 adrenal gland specimens, a total of 2 adrenal epithelioid angiosarcoma cases were identified. We reviewed the literature for 13 similar cases. All of the patients appeared to have morphological features of epithelioid cells including vascular endothelium immunophenotype, hemorrhage/necrosis, and anastomosing vascular channels. They underwent adrenalectomy without chemotherapy or radiotherapy. One was still well at 3-year follow up but the other had died at 1-month follow up. One of our cases was first described with accompanying reactive adrenal cortex hyperplasia in a local area. Moreover, the mechanisms of epithelioid angiosarcoma are still uncertain and require further study. Clinical prognosis is poor, therefore early accurate diagnosis and complete resection of this tumor may be very helpful for patients.
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Identifiers
31938388PMC6958267W3026213274What OpenQuestion holds
Registered trials
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