ArticleInternational journal of clinical and experimental pathology2018
Inflammatory infiltration and tissue remodeling in nasal polyps and adjacent mucosa of unaffected sinus.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Differential Immune Cell Infiltration in Eosinophilic and Non-Eosinophilic CRS: Correlations With Clinical, Endoscopic, and Radiological Findings.International forum of allergy & rhinology · 2025Article
- Balloon Eustachian Tuboplasty: A Systematic Review of Technique, Safety, and Clinical Outcomes in Chronic Obstructive Eustachian Tube Dysfunction.Healthcare (Basel, Switzerland) · 2025Review
- Single-cell RNA sequencing reveals the epithelial cell, fibroblast, and key gene alterations in chronic rhinosinusitis with nasal polyps.Scientific reports · 2024Article
- Differential Angiogenic Induction Impacts Nasal Polyp Tissue Growth.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- Characterization of the Notch pathway in nasal polyps of patients with chronic rhinosinusitis: A pilot study.Physiological reports · 2022Article
- Involvement of inflammatory cells in chronic rhinosinusitis with nasal polyps.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
- Histopathological parameters and immunoexpression of CD45RO (CLA) and CD68 in chronic rhinosinusitis with nasal polyps.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study was designed to explore the characteristics of inflammatory infiltration and tissue remodeling in the adjacent unaffected sinus mucosa of the polyp tissue (ANP).
methodsNasal polyps (NP) and ANP were obtained from 24 CRSwNP patients who received endoscopic sinus surgery. The frequency and distribution of Eosinophils, T lymphocytes (CD4+ T cells and CD8+ T cells), B lymphocytes, native macrophages, regulatory T cells and the total of inflammatory cells were detected by immunohistochemistry and hematoxylin-eosin stain. The thickness of the basal membrane was evaluated.
resultsMultivariate analysis of Variance (MANOVA) and F-tests were conducted for each independent variable between two groups. With test criterion alpha = 0.05, significant differences were observed between NP and ANP groups in terms of CD3 (F-Value = 10.47,
conclusionANP and NP may be one disease entity. Treg cells have impacts on the morphology of the tissues and might be a key factor in the further development of ANP.
Indexed as
Identifiers
31938386PMC6958245W3008121732What OpenQuestion holds
Registered trials
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