Genetic association of the polymorphisms in apoptosis-related genes with osteoarthritis susceptibility in Chinese Han population.

Gang Ma, Dianming Jiang, Jian Huang

Open access · greenAbstract read

In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it

0cells of the map it votes in

2citing papers in PubMed

–field-weighted citation impact, top 67% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

Metformin attenuates symptoms of osteoarthritis: role of genetic diversity of Bcl2 and CXCL16 in OA.Arthritis research & therapy · 2023
Trial
The Role of Functional Polymorphisms of ApoptoticIranian journal of medical sciences · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Gang MaDepartment of Orthopedics, First Affiliated Hospital, Chongqing Medical University Chongqing 400016, China.

Dianming JiangDepartment of Orthopedics, First Affiliated Hospital, Chongqing Medical University Chongqing 400016, China.

Jian HuangDepartment of Orthopedics, The Second Affiliated Hospital of Inner Mongolia Medical University Hohhot 010030, China.

Chongqing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApoptosis is a normal physiological process in organs development, but excessive apoptosis is pathological and harmful. In previous studies, apoptosis-related genes are considered to be involved in the onset of osteoarthritis, but the mechanism is unclear. Therefore, we selected two common polymorphisms of apoptosis-related genes (

methodsThe two polymorphisms were genotyped by polymerse chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 134 cases with osteoarthritis and 142 controls. These genotypes distributions in controls were checked whether conformed to Hardy-Weinberg equilibrium (HWE). χ

resultsThe χ

conclusions

Indexed as

apoptosisBAXBCL2osteoarthritispolymorphism

Identifiers

PMID31938334

PMCPMC6958211

OpenAlexW3026725122

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.