Evidence map›Paper›PMID 31938332›Full record

ArticleInternational journal of clinical and experimental pathology2018

Relationship between infiltrating lymphocytes in cancerous ascites and dysfunction of Cajal mesenchymal cells in the small intestine.

Xiuli Wang, Jing Li, Duanyang Liu, Lei Zhang, Baoshan Zhao, Jing Tang, Meisi Yan, Dan Kong, Xiaoming Jin

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 73% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xiuli WangDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Jing LiDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Duanyang LiuDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Lei ZhangDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Baoshan ZhaoDepartment of Pathology, Harbin Medical University Daqing, Heilongjiang, P. R. China.
Jing TangDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Meisi YanDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Dan KongDepartment of Gynecology, Third Affiliated Hospital of Harbin Medical University Harbin, Heilongjiang, P. R. China.
Xiaoming JinDepartment of Pathology, Harbin Medical University Harbin, Heilongjiang, P. R. China.
Harbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant ascites changes the microenvironment of the peritoneal cavity and damages abdominal functional host cells such as interstitial cells of Cajal (ICC), causing gastrointestinal dysfunction and poor prognosis. Besides tumor cells, malignant ascites contains large numbers of lymphocytes and macrophagocytes. These inflammatory cells act as a 'double arrow' and it is not clear whether they cause injury to ICCs. Our study demonstrates the presence of T lymphocytes in malignant ascites and shows that these cells may have a critical role in inducing damage to ICC via Caspases and Fas/FasL. These inflammatory cells were contributory to gastric dysfunction in our GI tumor-induced ascites mouse models.

Indexed as

apoptosisgastrointestinal dysfunctionsinterstitial cells of CajalMalignant ascitestumor associated lymphocytes

Identifiers

PMID31938332
PMCPMC6958188
OpenAlexW3011823615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.