Evidence map›Paper›PMID 31938251›Full record

ArticleInternational journal of clinical and experimental pathology2018

CD151 up-regulation contributes to the invasion of pituitary adenomas.

Shu Li, Chao Wu, Hongliang Gao, Xiuwei Wu, Le Yu, Bangbao Tao, Yun Hong

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Shu LiDepartment of Pathophysiology, Wannan Medical College Wuhu, China.
Chao WuDepartment of Pathophysiology, Wannan Medical College Wuhu, China.
Hongliang GaoDepartment of Pathophysiology, Wannan Medical College Wuhu, China.
Xiuwei WuDepartment of Medical Oncology, The Second Affiliated Hospital of Anhui Medical University Hefei, China.
Le YuDepartment of Pathophysiology, Wannan Medical College Wuhu, China.
Bangbao TaoDepartment of Neurosurgery, Xinhua Hospital, Shanghai Jiaotong University Shanghai 200092, China.
Yun HongDepartment of Ultrasonic Medicine, Yijishan Hospital, Wannan Medical College Wuhu 241001, China.
Wannan Medical College · CNAnhui Medical University · CNXinHua Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD151 is up-regulated in several types of tumors and is involved in tumor invasion and metastasis. However, the potential role of CD151 in pituitary adenomas remains unclear. Here, we performed quantitative real-time PCR and immunochemistry to measure the expression levels of CD151 in samples of pituitary adenomas and investigated the effects of CD151 knock-down on tumor phenotypes in the HP75 pituitary adenoma cell line. We found that, compared to normal pituitary tissues, CD151 expression is increased in non-invasive pituitary adenomas and further increased in invasive pituitary adenomas. CD151 knock-down inhibited cell proliferation, invasion, clone formation,

Indexed as

CD151invasionpituitary adenomastargeting therapy

Identifiers

PMID31938251
PMCPMC6958154
OpenAlexW3013609235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.