ArticleInternational journal of clinical and experimental pathology2018
LncRNA CCND2-AS1 is up-regulated and regulates proliferation, migration, and invasion in breast cancer.
Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 5 citations in OpenAlex.
- Beyond Junk DNA: Emerging Roles of Non-Coding RNAs in Cancer and Therapeutic Innovation.Biomolecules · 2026Review
- Identifying core genes in keloid and investigating immune infiltration and pan-cancer associations using eQTL and machine learning.Bioinformatics advances · 2025Article
- Unravelling the impact of aging on the human endothelial lncRNA transcriptome.Frontiers in genetics · 2022Article
- An interactive analysis of the mouse oviductal miRNA profiles.Frontiers in cell and developmental biology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many long non-coding RNAs (lncRNAs) have been found to exert influences on biological processes including tumorigenesis. Many lncRNAs have been reported as potential therapeutic targets and prognostic biomarkers in multiple cancers. CCND2 antisense RNA 1 (CCND2-AS1) is an lncRNA recently reported to be involved in the progression of glioma cancers. However, whether CCND2-AS1 is associated with progression of breast cancer remains unknown. In this study, quantitative real-time polymerase chain reaction (qRT-PCR) was used to measure CCND2-AS1 gene expression in breast cancer cell in lines. CCND2-AS1 expression was significantly over-expressed compared to normal breast epithelial cells. Gain-and loss-of-function experiments were performed
Indexed as
Identifiers
31938243PMC6958141W3027664785What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.