Evidence map›Paper›PMID 31938180›Full record

ArticleInternational journal of clinical and experimental pathology2018

Clinical significance of long non-coding RNA ZEB2-AS1 in locally advanced colorectal cancer.

Jianqiang Jin, Xinyi Zhou, Yan Qin, Weijia Wang, Haiun Lv, Suhua Xia, Xiaowei Qi

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in International journal of clinical and experimental pathology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jianqiang JinDepartment of Pathology, The Affiliated Hospital of Jiangnan University Wuxi, Jiangsu Province, P. R. China.
Xinyi ZhouDepartment of Pathology, The Affiliated Hospital of Jiangnan University Wuxi, Jiangsu Province, P. R. China.
Yan QinDepartment of Pathology, The Affiliated Hospital of Jiangnan University Wuxi, Jiangsu Province, P. R. China.
Weijia WangDepartment of Pathology, The Affiliated Hospital of Jiangnan University Wuxi, Jiangsu Province, P. R. China.
Haiun LvDepartment of Pathology, The Affiliated Hospital of Soochow University Suzhou, Jiangsu Province, P. R. China.
Suhua XiaDepartment of Oncology, The First Affiliated Hospital of Soochow University Suzhou, Jiangsu Province, P. R. China.
Xiaowei QiDepartment of Pathology, The Affiliated Hospital of Jiangnan University Wuxi, Jiangsu Province, P. R. China.
Jiangnan University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the clinical significance of differential expression of long non-coding RNA (lncRNA) ZEB2-AS1 in patients with colorectal cancer (CRC).

methodsmRNA expression of lncRNA ZEB2-AS1 was evaluated by real-time quantitative PCR on eighty-seven cancerous tissues and adjacent normal mucosal tissues from patients with CRC tissue. Correlation between the lncRNA ZEB2-AS1 expression and clinicopathological characteristics of the colorectal cancer patients was evaluated, and five-year overall survival (OS) was also analyzed according to the lncRNA ZEB2-AS1 expression of the CRC patients. Moreover, Cox Regression Analysis was performed in screening prognosis factors.

resultsA significantly upregulated lncRNA ZEB2-AS1 expression, with a fold change of 18.75, was found in CRC tissue compared to the normal tissue. lncRNA ZEB2-AS1 expression in CRC was correlated with death (

conclusionExpression of lncRNA ZEB2-AS1 was significantly upregulated in stage III CRC patients and affects the prognosis.

Indexed as

Colorectal cancerlncRNA ZEB2-AS1prognosis

Identifiers

PMID31938180
PMCPMC6957990
OpenAlexW3026303853

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.